Welcome to Santa Cruz Biotechnology!

Rosuvastatin Calcium Salt (CAS 147098-20-2)

(Based on popularity)

Synonym:(3R,5S,6E)-
Application:A selective and competitive inhibitor of HMG-CoA reductase
CAS Number:147098-20-2
Purity:≥99%
Molecular Weight:1001.14
Molecular Formula:C44H54F2N6O12S2•Ca
Refer to Certificate of Analysis for lot specific data (including water content).
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Rosuvastatin Calcium Salt sc-208316 10 mg $126
Description
A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic.
Technical Information
Appearance:Powder
Physical State:Solid
Solubility:Soluble in water (< 1 mg/ml at 25 °C), chloroform, DMSO (100 mg/ml at 25 °C), methanol, and ethanol (< 1 mg/ml at 25 °C).
Storage:Store at -20° C
Melting Point:151-156 °C
Refractive Index:n20D 1.60 (Predicted)
Optical Activity:α20/D +6.8º, c = 1 in methanol; α20/D -9.9º, c = 1 in chloroform; α20/D +14.8º, c = 1.012 in 50% MeOH
IC50:HMG-CoA reductase: IC50 = 2.1 nM (rat); HMGCRHMGCRHMGCR: IC50 = 3.1 nM (human); Liver microsomes: IC50 = 3.6 nM (rat); L6: IC50 = 65 nM (rat); Plasmodium falciparum: IC50 = 80 µM
Ki Data:HMGCRHMGCRHMGCR: Ki= 0.9 (human)
Safety and Reference Information
RTECS:MJ9675070
PubChem CID:6436658
MDL Number:MFCD04112702
SMILES:CC(C1=NC(=NC(=C1/C=C/[C@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O) C)C)C.CC(C1=NC(=NC(=C1/C=C/[C@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(= O)(=O)C)C)C.[Ca+2]
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),
SDS (MSDS)
Certificate of Analysis

Catalog Number

Lot Number

Related Product Categories