santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » GDP/GTP Binding Proteins » RhoGEF Antibody / RhoGEF Antibodies » RhoGEF p115/Lsc (H-165): sc-20804

RhoGEF p115/Lsc (H-165) Antibody: sc-20804

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 748-912 mapping at the C-terminus of RhoGEF p115 of human origin
  • recommended for detection of RhoGEF p115 of human origin and Lsc of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
 
Additional RhoGEF Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ARHGEF1 9138 19q13.2 NM_004706, NM_198977, NM_199002 Q92888
 601855
Mouse Arhgef1 16801 7 A3 Q61210
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
RhoGEF p115/Lsc (H-165) sc-20804 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RhoGEF p115 siRNA (h) sc-41734 10 µM $258
Lsc siRNA (m) sc-41725 10 µM $258
RhoGEF p115 (h)-PR sc-41734-PR 10 µM $23
Lsc (m)-PR sc-41725-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RhoGEF p115 shRNA Plasmid (h) sc-41734-SH 20 µg $520
Lsc shRNA Plasmid (m) sc-41725-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RhoGEF p115 shRNA (h) Lentiviral Particles sc-41734-V 200 µl $625
Lsc shRNA (m) Lentiviral Particles sc-41725-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RhoGEF p115 (h): 293T Lysate sc-113634 100µg/200µl $205
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
RhoGEF p115 (h4): 293T Lysate sc-175431 100µg/200µl $205
RhoGEF p115 (h3): 293T Lysate sc-175428 100µg/200µl $205

RhoGEF p115/Lsc Background Information
The Ras superfamily of GTPases can be subdivided into the Ras, Rho/Rac, Sar, Rab, Arf and Ran subfamilies and controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling, and cell growth. The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form. This activation is catalyzed by guanine nucleotide exchange factors (GEFs). The Dbl-related proteins are a large family of structurally related molecules that have a common ability to catalyze GEF activity for specific members of the Ras family. Dbl-related proteins include FGD1, RhoGEF p115/Lsc, Lfc, Lbc and Brx. RhoGEF p115/Lsc, Lbc and Lfc share sequence homology and show exchange activity toward Rho family GTPases. RhoGEF p115 (the human homolog of Lsc) catalyzes GEF activity for Rho but not Rac, Cdc42 or Ras GTPases.

RhoGEF p115/Lsc (H-165) Product Citations
See how others have used RhoGEF p115/Lsc (H-165): sc-20804 antibody and or RhoGEF p115/Lsc (H-165) antibody conjugates.


4 total citations
Loading citations.
 
RhoGEF p115/Lsc (H-165)
Click on image to enlarge
sc-20804
RhoGEF p115 of human origin and Lsc of mouse and rat origin (H-165): sc-20804. Western blot analysis of RhoGEF p115 expression in Jurkat whole cell lysate.
sc-20804
RhoGEF p115 of human origin and Lsc of mouse and rat origin (H-165): sc-20804. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing membrane and cytoplasmic staining of cells in white and red pulps at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-20804
RhoGEF p115 of human origin and Lsc of mouse and rat origin (H-165): sc-20804. Western blot analysis of RhoGEF p115 expression in HeLa whole cell lysate.
sc-20804
RhoGEF p115 of human origin and Lsc of mouse and rat origin (H-165): sc-20804. Western blot analysis of RhoGEF p115 expression in non-transfected: sc-117752 (A) and human RhoGEF p115 transfected: sc-113634 (B) 293T whole cell lysates.
sc-20804
RhoGEF p115 (H-165): sc-20804. Western blot analysis of RhoGEF p115 expression in non-transfected 293T: sc-117752 (A), human RhoGEF p115 transfected 293T: sc-175431 (B) and K-562 (C) whole cell lysates.
sc-20804
RhoGEF p115/Lsc (H-165): sc-20804. Western blot analysis of RhoGEF p115 expression in non-transfected 293T: sc-117752 (A), human RhoGEF p115 transfected 293T: sc-175428 (B), K-562 (C) and Jurkat (D) whole cell lysates.
Download
Datasheets
Get Adobe Acrobat Reader