t-Boc-MTSEA-Fluorescein (CAS 1042688-20-9)

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Application:	A thiol specific fluorescent probe useful in ion channel and protein topology research
CAS Number:	1042688-20-9
Molecular Weight:	628.67
Molecular Formula:	C₂₉H₂₈N₂O₁₀S₂

Description

t-Boc-MTSEA-Fluorescein is a thiol specific fluorescently labeled probe useful for ion channel and protein function and topology research due to the compounds ability to bind to cysteine residues found on proteins. t-Boc-MTSEA-Fluorescein may be applied in the real-time monitoring of conformational changes.

Technical Information

Appearance:	Yellow
Physical State:	Solid
Solubility:	Soluble in DMF, DMSO and Methanol
Storage:	Desiccate at -20° C
Fluoresence:	λex 492 nm, λem 515 nm

Safety and Reference Information

SMILES:

CC(C)(C)OC(=O)NC(CSS(C)(=O)=O)C(=O)NC1=CC=C(C(=C1)C(O)=O)C1=C2C=CC(=O)C=C2OC 2=C1C=CC(O)=C2

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Mannuzzu, L.M., et al. 1996. Science. 271: 213-216. PMID: 8539623
2. Adams, C.M., et al. 1998. J. Biol. Chem. 273: 30204-30207. PMID: 9804777
3. Stewart, A.K., et al. 2011. Am J Physiol Cell Physiol. [Epub ahead of print]. PMID: 21209359

SDS

Datasheet/SDS