Clavulanic acid potassium salt (CAS 61177-45-5)

Clavulanic acid potassium salt is a widely researched beta-lactamase inhibitor that has been a focal point in studies aiming to combat antibiotic resistance. In research environments, this compound is of particular interest due to its ability to inhibit a broad spectrum of beta-lactamases, enzymes produced by bacteria that render many antibiotics ineffective. Investigations involving clavulanic acid potassium salt delve into the structural and functional aspects of beta-lactamase inhibition, providing insights into how these enzymes interact with beta-lactam antibiotics and how inhibitors can enhance antibiotic efficacy. Additionally, it is employed in enzymology studies to understand the mechanism by which beta-lactamase inhibitors bind to their targets and protect antibiotics from degradation. This knowledge is for the design of new inhibitors that can be used in conjunction with antibiotics to overcome resistance. Moreover, the potassium salt form of clavulanic acid is particularly suited for such studies as it increases the compound′s solubility, making it more manageable in various experimental setups.