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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 94-168 mapping at the C-terminus of pleiotrophin (PTN) of human origin
- recommended for detection of PTN of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
PTN |
5764 |
7q33 |
NM_002825 |
P21246
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162095 |
| Mouse |
Ptn |
19242 |
6 B1 |
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P63089
|
N/A |
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PTN Background Information
Pleiotrophin (PTN) and midkine (MK) comprise a family of structurally related, developmentally regulated genes. Human PTN is synthesized as a 168 amino acid precursor which is subsequently cleaved to generate a 136 amino acid protein. Human PTN is approximately 50% identical to human MK, with conservation of all 10 cysteines. Cells reported to express PTN include osteoblasts, chondrocytes, fibroblasts, astrocytes, oligodendroglia, Schwann cells, neurons, pituicytes and Leydig cells. PTN is a heparin-binding growth factor that functions as a weak mitogen and promotes neurite outgrowth from embryonic brain neurons. PTN is expressed at high levels in many tissues during fetal development but becomes restricted to the brain in adult animals.
| PTN (H-75) Product Citations |
See how others have used PTN (H-75): sc-20716 antibody and or PTN (H-75) antibody conjugates.
3 total citations Loading citations.
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PTN (H-75)
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PTN (H-75): sc-20716. Western blot analysis of PTN expression in rat brain tissue extract.
PTN (H-75): sc-20716. Western blot analysis of PTN expression in rat brain tissue extract.
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