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1-Palmitoyl-sn-glycero-3-phosphocholine (CAS 17364-16-8)

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Alternate Names:
Lyso-PC
Application:
1-Palmitoyl-sn-glycero-3-phosphocholine is a phosphocholine for fluorescent probe design
CAS Number:
17364-16-8
Molecular Weight:
495.6
Molecular Formula:
C24H50NO7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that functions as a surfactant in experimental applications. It has the ability to reduce surface tension and stabilize emulsions. At the molecular level, 1-Palmitoyl-sn-glycero-3-phosphocholine interacts with lipid bilayers, affecting their structure and properties. It can also influence membrane fluidity and permeability, which is relevant in studies involving cell membranes and lipid-based systems.1-Palmitoyl-sn-glycero-3-phosphocholine has been observed to play a role in lipid metabolism and signaling pathways, contributing to the understanding of cellular processes. Its mechanism of action involves interactions with other lipids and proteins, impacting the overall behavior and function of biological membranes.


1-Palmitoyl-sn-glycero-3-phosphocholine (CAS 17364-16-8) References

  1. Effect of cholesterol on the formation of an interdigitated gel phase in lysophosphatidylcholine and phosphatidylcholine binary mixtures.  |  Lu, JZ., et al. 2001. J Biochem. 129: 891-8. PMID: 11388903
  2. Nonenzymatic synthesis of glycerolipids catalyzed by imidazole.  |  Testet, E., et al. 2002. J Lipid Res. 43: 1150-4. PMID: 12091500
  3. Molecular identification of lyso-glycerophosphocholines as endogenous immunosuppressives in bovine and rat gonadal fluids.  |  Foulds, LM., et al. 2008. Biol Reprod. 79: 525-36. PMID: 18509166
  4. Bilayers of arachidonic acid containing phospholipids studied by 2H and 31P NMR spectroscopy.  |  Rajamoorthi, K. and Brown, MF. 1991. Biochemistry. 30: 4204-12. PMID: 2021613
  5. Serum metabolomics of laryngeal cancer based on liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.  |  Zhang, X., et al. 2018. Biomed Chromatogr. 32: e4181. PMID: 29272549
  6. Phospholipids and UDP-glucuronosyltransferase. Structure/function relationships.  |  Zakim, D., et al. 1988. J Biol Chem. 263: 5164-9. PMID: 3128536
  7. Phase equilibria of the ternary system 1-palmitoyl-sn-glycero-3-phosphocholine/oleic acid/water studied by NMR.  |  Brentel, I., et al. 1987. Biochim Biophys Acta. 904: 401-4. PMID: 3663679
  8. Ether phospholipids as inhibitors of the arachidonoyl-CoA: 1-acyl-sn-glycero-3-phosphocholine acyltransferase in macrophages.  |  Herrmann, DB., et al. 1986. Biochim Biophys Acta. 876: 28-35. PMID: 3947667
  9. Reutilization of phosphatidylcholine analogues by the pulmonary surfactant system. The lack of specificity.  |  Jacobs, H., et al. 1984. Biochim Biophys Acta. 793: 300-9. PMID: 6546884
  10. Biosynthesis of pulmonary surfactant: comparison of 1-palmitoyl-sn-glycero-3-phosphocholine and palmitate as precursors of dipalmitoyl-sn-glycero-3-phosphocholine in adenoma alveolar type II cells.  |  Wykle, RL., et al. 1980. Arch Biochem Biophys. 199: 526-37. PMID: 6892673
  11. Specificity of lysophospholipase D.  |  Wykle, RL., et al. 1980. Biochim Biophys Acta. 619: 58-67. PMID: 7417469
  12. Arachidonic acid formed by peroxisomal beta-oxidation of 7,10,13,16-docosatetraenoic acid is esterified into 1-acyl-sn-glycero-3-phosphocholine by microsomes.  |  Baykousheva, SP., et al. 1994. J Biol Chem. 269: 18390-4. PMID: 8034586
  13. Alpha-tocopherol interacts with natural micelle-forming single-chain phospholipids stabilizing the bilayer phase.  |  Salgado, J., et al. 1993. Arch Biochem Biophys. 306: 368-76. PMID: 8215438

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Palmitoyl-sn-glycero-3-phosphocholine, 25 mg

sc-206203
25 mg
$75.00

1-Palmitoyl-sn-glycero-3-phosphocholine, 50 mg

sc-206203B
50 mg
$113.00

1-Palmitoyl-sn-glycero-3-phosphocholine, 100 mg

sc-206203A
100 mg
$251.00

1-Palmitoyl-sn-glycero-3-phosphocholine, 500 mg

sc-206203C
500 mg
$300.00