Adrenochrome (CAS 54-06-8)

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Application:	An inhibitor of catechol-o-methyltransferase
CAS Number:	54-06-8
Molecular Weight:	179.17
Molecular Formula:	C₉H₉NO₃

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
Adrenochrome	sc-206029	25 mg	$41
Adrenochrome	sc-206029A	250 mg	$245

Description

This compound is an oxidation product of adrenaline (ephinephrine, norepinephrine). It inhibits Catechol-O-methyltransferase (COMT), promotes the synthesis of prostaglandins in brain tissue in vitro, promotes the secretion of nerve growth factor by L-M cells, inhibits hexokinase and succinic dehydrog enase, and acts as a powerful stimulant of guanylcyclase activity in cell free systems. It is not clear which, if any, of these have physiological significance.

Technical Information

Appearance:	Red Crystalline Solid
Physical State:	Solid
Solubility:	50 mg in 1 mL 1M Sodium Hydroxide Gives a Dark Brown Solution
Storage:	Store at -20° C

Safety and Reference Information

PubChem CID:	5898
SMILES:	CN1CC(C2=CC(=O)C(=O)C=C21)O

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Costa, V.M., et al. 2007. Chem. Res. Toxicol., 20: 1183-1191. PMID: 17630707
2. Sotomayor-Zarate, R., et al. 2008. Biol. Reprod. 78: 673-680. PMID: 18077802

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SDS

Datasheet/SDS