Alizarin Red S (CAS 130-22-3)

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Synonym:	Sodium Alizarinesulfonate; Mordant Red 3; Alizarin Carmine
Application:	Used to determine the presence of calcific deposition by cells of an osteogenic lineage
CAS Number:	130-22-3
Molecular Weight:	342.26
Molecular Formula:	C₁₄H₇NaO₇S

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
Alizarin Red S	sc-205998	25 g	$53
Alizarin Red S	sc-205998A	100 g	$150

Description

Alizarin Red S is used in a biochemical assay to determine, quantitatively by colorimetry, the presence of calcific deposition by cells of an osteogenic lineage. Alizarin Red S has also been used as a histochemical stain for calcium in cells of non-osteogenic lineage and also a colorometric pH indicator in the range of 3.8-5.4.

Technical Information

Appearance:	Dark red powder
Physical State:	Solid
Solubility:	Soluble in water (1 mg/mL).
Storage:	Store at 4° C
Melting Point:	287-289 °C
Boiling Point:	430 °C
IC50:	Protein-tyrosine phosphatase 1B: IC₅₀ = 40 µM (human); Protein-tyrosine phosphatase 1: IC₅₀ = 48 µM (Saccharomyces cerevisiae S288c)
Color Index Number:	58005

Safety and Reference Information

WGK Germany:	3
RTECS:	CB1095300
PubChem CID:	3955344
Merck Index:	14: 8573
MDL Number:	MFCD00013049
EC Number:	204-981-8
Beilstein Registry:	4117090
SMILES:	C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)O)S(=O)(=O)[O-].[Na+]

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Bertoni, L., et al. 2009. J. Anat. 215: 577-583. PMID: 19682137
2. Verma, D., et al. 2010. Philos Transact A Math Phys Eng Sci. 368: 2083-2097. PMID: 20308116

SDS

Datasheet/SDS