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Vecuronium bromide (CAS 50700-72-6)

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Alternate Names:
Musculax; Norcuron
Application:
Vecuronium bromide is ompetes with acetylcholine and binds to cholinergic receptors
CAS Number:
50700-72-6
Purity:
≥98%
Molecular Weight:
637.74
Molecular Formula:
C34H57N2O4•Br
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Vecuronium bromide competes with acetylcholine and binds to cholinergic receptors at neuromuscular junctions. Vecuronium bromide is used in in vitro studies to assess the effects of Vecuronium bromides on cellular processes. It is used to study the effects of Vecuronium bromides on cell proliferation and differentiation, as well as on cell signaling pathways.


Vecuronium bromide (CAS 50700-72-6) References

  1. Vecuronium bromide, phenylephrine and atropine combinations as mydriatics in juvenile double-crested cormorants (Phalacrocorax auritus).  |  Loerzel, SM., et al. 2002. Vet Ophthalmol. 5: 149-54. PMID: 12236864
  2. Antagonism of vecuronium by one of its metabolites in vitro.  |  Khuenl-Brady, KS., et al. 1992. Eur J Pharmacol. 222: 153-6. PMID: 1361438
  3. A clinical study of intubating conditions under vecuronium bromide.  |  Betal, S., et al. 1991. J Indian Med Assoc. 89: 169-70. PMID: 1684201
  4. Stability of vecuronium in sterile water for injection stored in polypropylene syringes for 21 days.  |  Johnson, CE. and Cober, MP. 2007. Am J Health Syst Pharm. 64: 2356-8. PMID: 17989445
  5. Sympathetic influence on the pupillary light response in three red-eared slider turtles (Trachemys scripta elegans).  |  Dearworth, JR. and Cooper, LJ. 2008. Vet Ophthalmol. 11: 306-13. PMID: 19046290
  6. Biophysical study on the interaction of an anesthetic, vecuronium bromide with human serum albumin using spectroscopic and calorimetric methods.  |  Zhu, Y., et al. 2014. J Photochem Photobiol B. 140: 381-9. PMID: 25255425
  7. Interactions between calcium entry blockers and vecuronium bromide in anaesthetized cats.  |  Anderson, KA. and Marshall, RJ. 1985. Br J Anaesth. 57: 775-81. PMID: 2861838
  8. Disposition of vecuronium bromide in the cat.  |  Bencini, AF., et al. 1985. Br J Anaesth. 57: 782-8. PMID: 2861839
  9. Disposition and urinary excretion of vecuronium bromide in anesthetized patients with normal renal function or renal failure.  |  Bencini, AF., et al. 1986. Anesth Analg. 65: 245-51. PMID: 2869722
  10. Hepatobiliary disposition of vecuronium bromide in man.  |  Bencini, AF., et al. 1986. Br J Anaesth. 58: 988-95. PMID: 2875725
  11. Uptake and excretion of vecuronium bromide and pancuronium bromide in the isolated perfused rat liver.  |  Bencini, AF., et al. 1988. Anesthesiology. 69: 487-92. PMID: 2902816
  12. Vecuronium bromide and its advanced intermediates: A crystallographic and spectroscopic study.  |  Ciceri, S., et al. 2021. Steroids. 176: 108928. PMID: 34655596
  13. Inhibitory actions of vecuronium bromide on acetylcholine and glutamate responses at the frog and crayfish neuromuscular junction.  |  Shinozaki, H. and Ishida, M. 1984. Jpn J Pharmacol. 34: 299-306. PMID: 6144804
  14. Comparison of pancuronium and vecuronium for fetal neuromuscular blockade during invasive procedures.  |  Watson, WJ., et al. 1996. J Matern Fetal Med. 5: 151-4. PMID: 8796786
  15. An artificial neural network-based controller for the control of induced paralysis using vecuronium bromide.  |  Kamangar, FA. and Behbehani, K. 1997. Ann Biomed Eng. 25: 1040-51. PMID: 9395049

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Vecuronium bromide, 10 mg

sc-205880
10 mg
$86.00

Vecuronium bromide, 50 mg

sc-205880A
50 mg
$177.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This compound, Vecuronium bromide (CAS 50700-72-6), has an appearance of a white or off-white crystal or crystalline powder.
Answered by: Technical Support
Date published: 2017-01-11

Is this product supplied in a sterile vial? 

Asked by: two2igm05
Thank you for your question. No, this vial is not technically sterile or cell-culture grade. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2016-12-19
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Rated 5 out of 5 by from SearlSearl, TJ. et al. (PubMed 20880403) reported that ethanol interfered with the neuromuscular blocking action of Vecuronium. -SCBT Publication Review
Date published: 2015-07-07
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Vecuronium bromide is rated 5.0 out of 5 by 1.
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