Oxytetracycline (CAS 79-57-2)

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Application:	An antibiotic that impairs mitochondrial protein synthesis
CAS Number:	79-57-2
Purity:	≥98%
Molecular Weight:	460.43
Molecular Formula:	C₂₂H₂₄N₂O₉

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
Oxytetracycline	sc-205784	10 g	$40
Oxytetracycline	sc-205784A	50 g	$150

Description

Oxytetracycline is an anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis. Mechanistic studies show that this compound reduces cytochrome c activity which eventually causes cell growth arrest. Additionally, Oxytetracycline has demonstrated the ability to reduce murine bronchial inflammation. The anti-inflammatory characteristics of this agent are due to its ability to cause a decrease in IL-4, IL-5, IL-13, immune cells, and the ovalbumin-specific IgE. Data suggests that Oxytetracycline is also an inhibitor of NF-κB activation via phosphorylation and degradation of IκB-α.

Technical Information

Solubility:	Soluble in water
Storage:	Store at room temperature

Safety and Reference Information

PubChem CID:	5280972
SMILES:	CC1(C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O)O

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. van den Bogert, C., et al. 1981. Cancer Res. 41: 1943-1947. PMID: 7214362
2. van den Bogert, C., et al. 1983. Cancer Res. 43: 2247-2251. PMID: 6831447
3. Ci, X., et al. 2010. J. Clin. Immunol. [Epub ahead of print]. PMID: 21136283

SDS

Datasheet/SDS