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BIBB-515 (CAS 156635-05-1)

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Synonym:1-(4-Chlorobenzyl)-4-(4-(2-oxazolin-2-yl)benzylidene) piperidine
Application:An inhibitor of 2,3-oxidosqualene cyclase
CAS Number:156635-05-1
Molecular Weight:380.87
Molecular Formula:C22H21ClN2O2
Refer to Certificate of Analysis for lot specific data (including water content).
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Product NameCatalog #UnitPriceQtyAddFavorites
BIBB-515 sc-205602 10 mg $89
BIBB-515 sc-205602A 50 mg $368
BIBB-515 is a potent and selective inhibitor of OSC (2,3-oxidosqualene cyclase) that has displayed inhibitory action against LDL production.
Technical Information
Physical State:Solid
Solubility:Soluble in DMSO (2 mg/mL), DMF (8 mg/mL), and EtOH (~0.15).
Storage:Store at room temperature
Melting Point:174.5-176 °C
Boiling Point:586.53 °C at 760 mmHg
Density:1.27 g/cm3
Refractive Index:n20D 1.63 (lit.)
IC50:Lanosterol synthase: IC50 = 36 nM (human)
Safety and Reference Information
PubChem CID:501398
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
1. Eisele, B., et al. 1997. J. Lipid Res. 38: 564-575. PMID: 9101437
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