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6-Thioguanine (CAS 154-42-7)

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Application:An immunosuppressive, anti-neoplastic, and anti-cancer
CAS Number:154-42-7
Molecular Weight:167.19
Molecular Formula:C5H5N5S
Refer to Certificate of Analysis for lot specific data (including water content).
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
6-Thioguanine sc-205587 250 mg $40
6-Thioguanine sc-205587A 500 mg $69
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Description
6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.
Technical Information
Physical State:Solid
Derived from:Synthetic
Solubility:Soluble in DMSO (100 mM).
Storage:Store at -20° C
Melting Point:>300 °C (lit.)(dec.)
Boiling Point:555.40 °C at 760 mmHg (Predicted)
Density:2.08 g/cm3 (Predicted)
Refractive Index:n20D 2.07 (Predicted)
Safety and Reference Information
Transport:UN 3249, Class 6.1, Packing group III
WGK Germany:3
RTECS:UP0740000
PubChem CID:2723601
Merck Index:14: 9337
MDL Number:MFCD00233553
EC Number:205-827-2
Beilstein Registry:157765
SMILES:C1=NC2=C(N1)C(=S)N=C(N2)N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
Karran P. Br Med Bull 79-80: 153-70 (2006). Sartorelli AC, Booth BA. Cancer Res. 25: 1393-40 (1965).
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