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CPTI Antibody (N-17): sc-20514

 |  Datasheet

(Based on data analysis)
  • CPTI Antibody (N-17) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an N-terminal cytoplasmic domain of CPTI of human origin
  • recommended for detection of CPTI, liver isoform (CPTI-L) and muscle isoform (CPTI-M) of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-20514 P
  • See 4 citations for CPTI Antibody (N-17)
 

See additional Carnitine Acetyltransferase Antibodies including Carnitine Acetyltransferase, CPTI, CPTI-L, CPTI-M and CPTII.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CPTI Antibody (N-17) sc-20514 200 µg/ml $279
CPTI (N-17) P sc-20514 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CPTI siRNA (h) sc-40376 10 µM $258
CPTI siRNA (m) sc-40377 10 µM $258
CPTI siRNA (r) sc-156134 10 µM $258
CPTI (h)-PR sc-40376-PR 10 µM, 20 µl $23
CPTI (m)-PR sc-40377-PR 10 µM, 20 µl $23
CPTI (r) -PR sc-156134-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CPTI shRNA Plasmid (h) sc-40376-SH 20 µg $520
CPTI shRNA Plasmid (m) sc-40377-SH 20 µg $520
CPTI shRNA Plasmid (r) sc-156134-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CPTI shRNA (h) Lentiviral Particles sc-40376-V 200 µl $625
CPTI shRNA (m) Lentiviral Particles sc-40377-V 200 µl $625
CPTI shRNA (r) Lentiviral Particles sc-156134-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CPT1A 1374 11q13.2 NM_001031847, NM_001876 P50416
 600528
Mouse Cpt1a 12894 19 A P97742
 N/A
Mouse Cpt1b 12895 15 E3 Q924X2
 N/A
 

The mitochondrial ∫-oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase (CPT) I (outer membrane and detergent labile) and II (inner membrane and detergent stable), together with carnitine carrier. CPTI catalyzes the first reaction in the transport of long-chain fatty acids from the cytoplasm to the mitochondrion, a rate-limiting step in beta-oxidation. Two types of CPTI are known, the liver (CPTIA) and muscle (CPTIB) isoforms. The muscle type protein is specially expressed in heart and skeletal muscle. Membrane-bound CPTI, but not CPTII, is inhibited reversibly by malonyl-coenzyme A (CoA). Unlike CPTII, CPTI requires membrane integrity for catalytic function. In addition, glutamic acid 3 and histidine 5 are necessary for malonyl CoA inhibition and binding to liver CPTI, but not for catalytic activity.

CPTI Antibody (N-17) Product Citations
See how others have used CPTI Antibody (N-17) and or CPTI Antibody (N-17) conjugates.


4 total citations
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