Molecular structure of Ferulic acid, CAS Number: 1135-24-6
Ferulic acid (CAS 1135-24-6)
See product citations (10)
Alternate Names:
4-Hydroxy-3-methoxycinnamic acid
Application:
Ferulic acid is a chemopreventive analog of caffeic acid and inhibitor of 5-LO and 12-LO
CAS Number:
1135-24-6
Molecular Weight:
194.18
Molecular Formula:
C10H10O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ferulic acid is a chemopreventive caffeic acid analogue. Ferulic acid is an inhibitor of 5-LO (5-lipoxygenase) and 12-LO (12-lipoxygenase). Ferulic acid is recognized for its potential as an antioxidant, as it effectively neutralizes free radicals and diminishes oxidative stress. Moreover, it is known to exhibit anti-inflammatory attributes by impeding the generation of pro-inflammatory cytokines. Additionally, it has been observed to impede the advancement of cancer cells by disrupting the progression of the cell cycle.
Ferulic acid (CAS 1135-24-6) References
- Ferulic acid and its position among the phenolic compounds of wheat. | Klepacka, J. and Fornal, Ł. 2006. Crit Rev Food Sci Nutr. 46: 639-47. PMID: 17092829
- Relevance, structure and analysis of ferulic acid in maize cell walls. | Bento-Silva, A., et al. 2018. Food Chem. 246: 360-378. PMID: 29291861
- Antioxidant Properties of Ferulic Acid and Its Possible Application. | Zduńska, K., et al. 2018. Skin Pharmacol Physiol. 31: 332-336. PMID: 30235459
- Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase. | Zheng, Y., et al. 2020. Food Chem. 317: 126346. PMID: 32070843
- Nephroprotective effect of ferulic acid on gentamicin-induced nephrotoxicity in female rats. | Erseçkin, V., et al. 2022. Drug Chem Toxicol. 45: 663-669. PMID: 32354291
- Ferulic Acid Activity in Topical Formulations: Technological and Scientific Prospecting. | Cavalcanti, GR., et al. 2021. Curr Pharm Des. 27: 2289-2298. PMID: 33081675
- Ferulic acid promotes muscle glucose uptake and modulate dysregulated redox balance and metabolic pathways in ferric-induced pancreatic oxidative injury. | Salau, VF., et al. 2022. J Food Biochem. 46: e13641. PMID: 33555086
- Ferulic acid loaded microspheres reinforced in 3D hybrid scaffold for antimicrobial wound dressing. | Sivakumar, S., et al. 2021. Int J Biol Macromol. 177: 463-473. PMID: 33609580
- Ferulic acid prevents cyclosporine-induced nephrotoxicity in rats through exerting anti-oxidant and anti-inflammatory effects via activation of Nrf2/HO-1 signaling and suppression of NF-κB/TNF-α axis. | Nouri, A., et al. 2022. Naunyn Schmiedebergs Arch Pharmacol. 395: 387-395. PMID: 35092471
- Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity. | DiNicolantonio, JJ., et al. 2022. Open Heart. 9: PMID: 35301252
- Ferulic acid nanocapsules as a promising treatment modality for colorectal cancer: Preparation and in vitro/in vivo appraisal. | El-Gogary, RI., et al. 2022. Life Sci. 298: 120500. PMID: 35341825
- Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway. | Zhang, D., et al. 2022. Phytomedicine. 106: 154420. PMID: 36115115
- Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells. | Wang, J., et al. 2022. Food Res Int. 161: 111816. PMID: 36192955
Inhibitor of:
β-defensin 135, 12-LO, 4-HNE, 5-LO, Aflatoxin B2, ALDH3B1, cystatin 11, Doc2g, MDA5, NALP5, Nitrotyrosine, TRP1, and Tyrosinase.Activator of:
α-defensin 2, β-Glucoronidase, β-glucosidase, γ-GCSm, ALDH2, C11orf59, C20orf111, CYBASC3, DHRS3, FRP-1, GALC, GPx-4, GPx-8, Grx1, Hct1, HNP-1, KRTAP13-4, KRTAP8-2, lactoferrin, Lce1m, LCE3E, LPO, MAWDBP, MetAP-2, Mox1, NDOR1, Nucleoredoxin, Oas1f, OTTMUSG00000018259, PGs2_5730494M16Rik, PON3, PRX I, PRX2, RTCD1, SERCA1, SPAG11B, SPATA18, Sptrx-1, SVCT2, TXNL6, and Vitronectin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ferulic acid, 5 g | sc-204753 | 5 g | $42.00 | |||
Ferulic acid, 25 g | sc-204753A | 25 g | $62.00 | |||
Ferulic acid, 100 g | sc-204753B | 100 g | $153.00 | |||
Ferulic acid, 500 g | sc-204753C | 500 g | $552.00 | |||
Ferulic acid, 1 kg | sc-204753D | 1 kg | $988.00 |