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Baicalin (CAS 21967-41-9)

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Application:A flavonoid compound with antioxidant effects
CAS Number:21967-41-9
Molecular Weight:446.37
Molecular Formula:C21H18O11
Refer to Certificate of Analysis for lot specific data (including water content).
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Baicalin sc-204638 1 mg $68
Baicalin sc-204638A 5 mg $268
Description
Baicalin is a flavonoid compound with anti-inflammatory and anti-oxidant activity extracted from Scutellarua rivularis. HIV studies show that Baicalin inhibits HIV-1 replication by blocking the activity of the reverse transcriptase (HIV-1 RT). Baicalin has been suggested by Neural Stem cell studies to act as a strong inducer of neural differentiation by activating Erk1/2. Additionally, Baicalin was reported to inhibit the up-regulation of the connective tissue growth factor, and blocks the TLR2/4 signaling pathway. Baicalin is an inhibitor of PREP.
Technical Information
Appearance:Crystalline powder
Physical State:Solid
Solubility:Soluble in water (<1 mg/ml at 25 °C), DMF, DMSO (89 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
Storage:Store at -20° C
Melting Point:202-205 °C (lit.)(dec.)
Boiling Point:836.62 °C at 760 mmHg (Predicted)
Density:1.74 g/cm3
Refractive Index:n20D 1.74
Optical Activity:α20/D -85º, c = 1 in DMSO
Safety and Reference Information
WGK Germany:3
RTECS:LZ5776910
PubChem CID:64982
MDL Number:MFCD00134418
SMILES:C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Lin, C.C. and Shieh, D.E. 1996. Am. J. Chin. Med. 24: 31-36. PMID: 8739179
2. Kitamura, K., et al. 1998. Antiviral Res. 37: 131-140. PMID: 9588845
3. Tu, X.K., et al. 2010. Inflammation. PMID: 20859668
4. Jia, H., et al. 2010. Sheng Li Xue Bao. 62: 535-540. PMID: 21170500
5. Li, M., et al. 2011. Chembiochem. [Epub ahead of print]. PMID: 21207428
SDS (MSDS)
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