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WHI-P180, Hydrochloride (CAS 211555-08-7)

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Application:An IgE-mediated mast cell response inhibitor
CAS Number:211555-08-7
Molecular Weight:333.77
Molecular Formula:C16H15N3O3 HCl
Refer to Certificate of Analysis for lot specific data (including water content).
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Product NameCatalog #UnitPriceQtyAddFavorites
WHI-P180, Hydrochloride sc-204396 500 µg $117
WHI-P180, Hydrochloride sc-204396A 1 mg $298
WHI-P180, Hydrochloride is a potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo. WHI-P180, Hydrochloride also inhibits cyclin-dependent kinase 2 (Cdk2; IC50 = 1 μM) by blocking the ATP site.
Technical Information
Physical State:Solid
Solubility:Soluble in DMSO (50 mg/ml).
Storage:Store at 4° C
Refractive Index:n20D 1.69 (Predicted)
IC50:PI 3-kinase p85α: IC50 = 2 nM (human); Flt-1: IC50 = 200 nM (human); Flk-1: IC50 = 50 nM (human); Cdk2: IC50 = 1 µM (human); Flg: IC50 = 11 µM (human)
Safety and Reference Information
PubChem CID:5687
MDL Number:MFCD09026915
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Shewchuk, L., et al. 2000. J. Med. Chem. 43, 133. Chen, C.L., et al. 1999. Pharm. Res. 16, 117.
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