PKR Inhibitor, Negative Control (CAS 852547-30-9)

The PKR inhibitor is a compound that targets and inhibits the activity of the protein kinase R (PKR) enzyme. This inhibition prevents the phosphorylation of its downstream targets, thereby disrupting the cellular signaling pathways involved in the regulation of gene expression and protein synthesis. By interfering with PKR′s function, the inhibitor disrupts the cellular response to various stress stimuli, such as viral infection or cellular damage. This disruption can be utilized in applications to investigate the specific role of PKR in cellular processes its molecular interactions with other cellular components. The inhibitor′s mechanism of action involves binding to the active site of PKR, thereby preventing its activation and subsequent downstream signaling. This interference with PKR′s activity can provide insights into the molecular mechanisms underlying cellular stress responses and may contribute to a better understanding of the role of PKR in various cellular processes.