Date published: 2025-12-25

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MreB Perturbing Compound A22 (CAS 22816-60-0)

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Alternate Names:
{[(3,4-dichlorophenyl)methyl]sulfanyl}methanimidamide hydrochloride
Application:
MreB Perturbing Compound A22 is an isothiourea that reversibly perturbs MreB function
CAS Number:
22816-60-0
Purity:
≥90%
Molecular Weight:
271.6
Molecular Formula:
C8H8Cl2N2S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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MreB Perturbing Compound A22 is a molecule used in microbiological and cell biology research to study the bacterial cytoskeleton. MreB, a homolog of actin in prokaryotes, is essential for maintaining the shape and cellular integrity of many rod-shaped bacteria. MreB Perturbing Compound A22 specifically disrupts the polymerization of MreB, leading to defects in cell morphology and providing researchers with a tool to examine the role of MreB in bacterial cell growth and division. By using MreB Perturbing Compound A22, studies can dissect the molecular pathways that govern cell wall synthesis and how these processes are coordinated with the cell cycle.


MreB Perturbing Compound A22 (CAS 22816-60-0) References

  1. Super-resolution imaging and tracking of protein-protein interactions in sub-diffraction cellular space.  |  Liu, Z., et al. 2014. Nat Commun. 5: 4443. PMID: 25030837
  2. Topologically-guided continuous protein crystallization controls bacterial surface layer self-assembly.  |  Comerci, CJ., et al. 2019. Nat Commun. 10: 2731. PMID: 31227690
  3. Two different cell-cycle processes determine the timing of cell division in Escherichia coli.  |  Colin, A., et al. 2021. Elife. 10: PMID: 34612203

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MreB Perturbing Compound A22, 25 mg

sc-204100
25 mg
$178.00