MDL 11,939 CAS (107703-78-6) sc-204069

santa cruz biotechnology, inc.

MDL 11,939: sc-204069	\| Datasheet \| MSDS

Specifications
- Offered as 10 mg (sc-204069) and 50 mg (sc-204069A) sizes
- CAS Number: 107703-78-6
- Molecular Weight: 295.42
- Molecular Formula: C₂₀H₂₅NO
- Purity: >99%
- Physical Appearance: White solid
- Solubility: Soluble to 50 mM in 1eq. HCl and to 50 mM in Ethanol and to 50 mM in DMSO
- SMILES: C1CN(CCC1C(C2=CC=CC=C2)O)CCC3=CC=CC=C3
Description
- Potent, selective and orally active 5-HT2 receptor antagonist (Ki values are 0.54 and 81.6 nM at 5-HT2A and 5-HT2C receptors respectively).
For Research Use Only
Reference Numbers
- PubChem Compound ID: 71781
References
- Dudley et al (1988) Pharmacological effects of MDL 11,939: a selective, centrally acting antagonist of 5-HT2 receptors. Drug Dev.Res. 13 29. Schmidt et al (1991) 5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-Dopa. J.Pharmacol.Exp.Ther. 256 230. Aloyo and Harvey (2000) Antagonist binding at 5-HT2A and 5-HT2C receptors in the rabbit: high correlation with the profile for the human receptors. Eur.J.Pharmacol. 406 163.