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7-Deacetyl-7-O-hemisuccinyl-Forskolin (CAS 83797-56-2)

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Synonym:4-[(3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl)oxy]-4-oxobutanoic acid
Application:A forskolin derivative
CAS Number:83797-56-2
Molecular Weight:468.6
Molecular Formula:C24H36O9
Refer to Certificate of Analysis for lot specific data (including water content).
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
7-Deacetyl-7-O-hemisuccinyl-Forskolin sc-203959 1 mg $200
7-Deacetyl-7-O-hemisuccinyl-Forskolin sc-203959A 5 mg $875
Description
7-Deacetyl-7-O-hemisuccinyl-Forskolin is a forskolin derivative that can be readily activated and used for preparation of affinity supports and probes. It can be coupled to aminoethyl-agarose via its N-hydroxysuccinimide ester. The immobilized derivative can be used to purify adenylate cyclase; activates A cyclase (adenylate cyclase) (EC50 = 50 μM).
Technical Information
Physical State:Solid
Solubility:Soluble in water, ethanol, methanol, and DMSO (5 mg/ml).
Storage:Store at -20° C
Melting Point:258.65 °C (Predicted)
Boiling Point:625.45 °C at 760 mmHg (Predicted)
Density:1.31 g/cm3 (Predicted)
Refractive Index:n20D 1.57 (Predicted)
IC50:adenylate cyclase: EC5050 = 50 µM
Safety and Reference Information
WGK Germany:3
PubChem CID:4114878
MDL Number:MFCD00036869
SMILES:CC1(CCC(C2(C1C(C(C3(C2(C(=O)CC(O3)(C)C=C)O)C)OC(=O)CCC(=O)O)O)C)O)C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
Pfeuffer, T., et al. 1983. FEBS Lett. 164, 154. Huang, R., et al. 1982. J. Cyclic Nucleotide Res. 8, 385. Pfeuffer, T., and Metzger, H. 1982. FEBS Lett. 146, 369.
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