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home » Chemicals » Inhibitors - Other » BIBR 1532: sc-203843

BIBR 1532: sc-203843

  |  Datasheet  | MSDS
  • Specifications
    • Offered as 10 mg (sc-203843) and 50 mg (sc-203843A) sizes
    • CAS Number: 321674-73-1
    • Molecular Weight: 331.37
    • Molecular Formula: C21H17NO3
    • Purity: ≥98%
    • Solubility: Soluble to 100 mM in DMSO and to 25 mM in Ethanol
    • SMILES: C/C(=C\C(=O)NC1=CC=CC=C1C(=O)O)/C2=CC3=CC=CC=C3C=C
      2
  • Description
    • BIBR 1532 is a compound suggested to act as a selective and specific telomerase inhibitor. Studies indicate that BIBR 1532 inhibits the reverse transcriptase of telomerase, hTERT, and shortens the length of the telomere. In addition, reports indicate that BIBR 1532 has the ability to stop cell proliferation in lung cancer cell studies after 120 days.
  • Storage
    • Store at room temperature
  • Safety
    • Safety Statements: 22-24/25-36/37/39
  • For Research Use Only
  • Reference Numbers
  • References
    • 1. Damm, K., et al. 2001. EMBO J. 20: 6958-6968. PMID: 11742973
      2. Barma, D.K., et al. 2003. Bioorg. Med. Chem. Lett. 13: 1333-1336. PMID: 12657276
      3. Phatak, P. and Burger, A.M. 2007. Br. J. Pharmacol. 152: 1003-1011. PMID: 17603541
      4. Rankin, A.M., et al. 2008. Anticancer Drugs. 19: 329-338. PMID: 18454043
      5. Parsch, D., et al. 2008. Cancer Invest. 26: 590-596. PMID: 18584350
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
BIBR 1532 sc-203843 10 mg $145
BIBR 1532 sc-203843A 50 mg $615
BIBR 1532
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BIBR 1532
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