Sudan IV (CAS 85-83-6)

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Synonym:	Fat Ponceau R or 4
Application:	A red β-naphthol diazo dye used for staining triglycerides, lipids and lipoproteins in cells and tissues
CAS Number:	85-83-6
Molecular Weight:	380.45
Molecular Formula:	C₂₄H₂₀N₄O

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
Sudan IV	sc-203762	25 g	$37
Sudan IV	sc-203762A	100 g	$78

Description

Sudan IV, also called Scarlet red and Fat Ponceau R, is a fat-soluble dye often used for staining triglycerides, lipids and lipoproteins present in cells and tissues. This red β-naphthol diazo dye has the same basic structure as Sudan III with two added methyl groups increasing the deepness and intensity of the stain. Sudan dyes are a group of lipid soluble solvent dyes often called lysochromes. With the use of certain solvents, may also be used to stain some protein bound lipids in paraffin sections. It is less popular than Oil Red O (sc-203749) as it has a more orange shade. Sudan I (sc-215922), Sudan III (sc-203761), and Sudan IV (sc-203762) have been classified as category 3 carcinogens by the International Agency for Research on Cancer.

Technical Information

Appearance:	Dark red to red-brown powder
Physical State:	Solid
Solubility:	Soluble in chloroform at 1 mg/mL. Soluble in water at 0.1 mg/mL. Very soluble in benzene, methanol, acetone, bydrocarbon solvents, oils, fats and waxes.
Storage:	Store at room temperature
Melting Point:	181-188
Boiling Point:	618.85ºC
Density:	1.192 g/cm3
Refractive Index:	1.645
Color Index Number:	26105

Safety and Reference Information

WGK Germany:	3
RTECS:	QL5775000
PubChem CID:	5876571
Merck Index:	14: 8393
MDL Number:	MFCD00003893
EC Number:	201-635-8
Beilstein Registry:	709018
SMILES:	CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NN=C3C(=O)C=CC4=CC=CC=C43)C

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Xiao, W., et al. 2003. J. Nucl. Med. 44: 770-773. PMID: 12732679
2. Li, L., et al. 2007. BMC Struct. Biol. 7: 16. PMID: 17389047
3. Mulvihill, E.E., et al. 2010. Arterioscler. Thromb. Vasc. Biol. 30: 742-748. PMID: 20110573
4. Refat, N.A., et al. 2008. J. Biochem. Mol. Toxicol. 22: 77-84. PMID: 18418879

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