Phenol Red (CAS 143-74-8)

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Synonym:	Phenolsulfonphthalein
Application:	Used in culture media, phenol red identifies pH changes from neutral (red) to acidic (yellow) values
CAS Number:	143-74-8
Dye Content:	≥95%
Molecular Weight:	354.38
Molecular Formula:	C₁₉H₁₄O₅S

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
Phenol Red	sc-203752	5 g	$20
Phenol Red	sc-203752A	25 g	$51

Description

Phenol Red is a compound widely used in culture media which identifies pH changes from neutral (red) to acidic (yellow) values. Typically a change in color from red to yellow indicates high rates of cellular death when used in tissue cultures. In the culture of breast cancer cells Phenol Red has been observed to act as a weak estrogen. In human MCF-7 cells, phenol red has reduced Roscovitine (sc-24002) mediated cell cycle arrest and apoptosis. Phenol red has also induced oogenesis from cells scraped from the surface of adult ovaries.

Technical Information

Appearance:	Dark red to dark brown powder
Physical State:	Solid
Solubility:	Soluble in 1M NaOH at 1 mg/mL and Water
Storage:	Store at room temperature

Safety and Reference Information

RTECS:	SJ7490000
PubChem CID:	4766
Merck Index:	7247
MDL Number:	MFCD00003552
Beilstein Registry:	326470
SMILES:	OC1=CC=C(C=C1)C1(OS(=O)(=O)C2=C1C=CC=C2)C1=CC=C(O)C=C1

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Berthois, Y., et al. 1986. Proc. Natl. Acad. Sci. U.S.A. 83: 2496-2500. PMID: 3458212
2. Bukovsky, A., et al. 2005. Reprod. Biol. Endocrinol. 3: 17. PMID: 15871747
3. Wesierska-Gadek, J., et al. 2006. J. Cell. Biochem. 98: 1367-1379. PMID: 16741967

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SDS

Datasheet/SDS