Solubility: Soluble to 100 mM in Ethanol and to 100 mM in DMSO
SMILES: C1=CC(=CC(=C1)Cl)C=N/N=C/C2=CC(=CC=C2)Cl
Description
Allosteric ligand for the metabotropic glutamate receptor mGlu5; displays neutral modulation. Does not affect agonist-stimulated mGlu5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB and DMeOB.
