AH 11110 hydrochloride (CAS 179388-65-9)

Application:	A subtype-selective ligand for the α1B-AR
CAS Number:	179388-65-9
Molecular Weight:	374.91
Molecular Formula:	C₂₁H₂₆N₂O₂•HCl

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
AH 11110 hydrochloride	sc-203502	10 mg	$115
AH 11110 hydrochloride	sc-203502A	50 mg	$497

Description

AH 11110 hydrochloride is a subtype-selective ligand for the α1B-adrenoceptor (α1B-AR). The pK_i values for binding to rat fibroblast cell membranes expressing α1B (hamster), α1A (bovine) and α1D (rat) are 7.1, 5.59, and 5.68 respectively. AH 11110 hydrochloride appears to be non-selective between α1 subtypes and α2 receptors in smooth muscle preparations.

Technical Information

Appearance:	White
Physical State:	Solid
Solubility:	Soluble to 25 mM in Water
Storage:	Store at room temperature

Safety and Reference Information

PubChem CID:	9907616
SMILES:	C1CCN(CC1)C(=N)CC(COC2=CC=CC=C2C3=CC=CC=C3)O.Cl

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Saussy, D.L., et al. 1996. J. Pharmacol. Exp. Ther. 278: 136-144. PMID: 8764344
2. Eltze, M., et al. 2001. Eur. J. Pharmacol. 415: 265-276. PMID: 11275009

SDS

Datasheet/SDS