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Gentamicin sulfate (CAS 1405-41-0)

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Alternate Names:
Gentamicin sulfate also known as Alcomicin; Bristagen; Cidomycin; Duragentam; Garamycin; Garasol; Genoptic; Gentacidin; Gentacin; Gentaglyde; Gentalyn; Gentamicin C Complex Citrate; Gentibioptal; Genticin; Gentocin; Gentogram; Gent-Ophtal; Getalline; GM Sulfate
Application:
Gentamicin sulfate is a useful broad-spectrum cell culture antibiotic which inhibits protein synthesis
CAS Number:
1405-41-0
Molecular Weight:
575.67
Molecular Formula:
C21H43N5O7•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Gentamicin sulfate inhibits protein synthesis by binding to L6 protein and 50S ribosomal subunit. Gentamicin sulfate is reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Gentamicin sulfate is reported to have low toxicity to mammalian cells and viruses at certain concentrations, and Gentamicin sulfate is useful for long-term tissue culture studies with viruses. This compound is a mixture of Gentamycin c1, c1a and c2.


Gentamicin sulfate (CAS 1405-41-0) References

  1. Effects of gentamicin sulfate on enzyme activities of carbonic anhydrase from human erythrocytes in vitro and from rat erythrocytes in vivo.  |  Beydemir, S., et al. 2002. Biol Pharm Bull. 25: 966-9. PMID: 12186427
  2. Effects of gentamicin sulfate on the contractility of myometrium isolated from non-pregnant cows.  |  Ocal, H., et al. 2004. Anim Reprod Sci. 84: 269-77. PMID: 15302370
  3. Gentamicin interaction with Pseudomonas aeruginosa cell envelope.  |  Martin, NL. and Beveridge, TJ. 1986. Antimicrob Agents Chemother. 29: 1079-87. PMID: 2425732
  4. Bacterial Contamination of Boar Semen and its Relationship to Sperm Quality Preserved in Commercial Extender Containing Gentamicin Sulfate.  |  Gączarzewicz, D., et al. 2016. Pol J Vet Sci. 19: 451-459. PMID: 27760038
  5. Antibacterial and anticancer activities of asymmetric lollipop-like mesoporous silica nanoparticles loaded with curcumin and gentamicin sulfate.  |  Cheng, Y., et al. 2020. Colloids Surf B Biointerfaces. 186: 110744. PMID: 31874345
  6. Novel CdS/MOF Cathodic Photoelectrochemical (PEC) Platform for the Detection of Doxorubicin Hydrochloride and Gentamicin Sulfate.  |  Dong, W., et al. 2021. ACS Appl Mater Interfaces. 13: 57497-57504. PMID: 34807581
  7. Effect of intra-articular gentamicin sulfate on normal equine synovial membrane.  |  Stover, SM. and Pool, RR. 1985. Am J Vet Res. 46: 2485-91. PMID: 4083580
  8. Evaluation of the in vitro activity of tobramycin as compared with that of gentamicin sulfate.  |  Traub, WH. and Raymond, EA. 1972. Appl Microbiol. 23: 4-7. PMID: 4621796
  9. Ototoxicity assessment of a gentamicin sulfate otic preparation in dogs.  |  Strain, GM., et al. 1995. Am J Vet Res. 56: 532-8. PMID: 7785834
  10. Leupeptin and E-64, inhibitors of cysteine proteinases, prevent gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts.  |  Montenez, JP., et al. 1994. Toxicol Lett. 73: 201-8. PMID: 8091428
  11. Intravesical instillation of gentamicin sulfate: in vitro, rat, canine, and human studies.  |  Wan, J., et al. 1994. Urology. 43: 531-6. PMID: 8154077
  12. Quantitation of gentamicin sulfate in injectable solutions by capillary electrophoresis.  |  Flurer, CL. and Wolnik, KA. 1994. J Chromatogr A. 663: 259-63. PMID: 8173668
  13. Surface action of gentamicin on Pseudomonas aeruginosa.  |  Kadurugamuwa, JL., et al. 1993. J Bacteriol. 175: 5798-805. PMID: 8376327

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Gentamicin sulfate, 1 g

sc-203334
1 g
$55.00

Gentamicin sulfate, 5 g

sc-203334A
5 g
$175.00

Gentamicin sulfate, 50 g

sc-203334F
50 g
$499.00

Gentamicin sulfate, 100 g

sc-203334B
100 g
$720.00

Gentamicin sulfate, 1 kg

sc-203334C
1 kg
$1800.00

Gentamicin sulfate, 2.5 kg

sc-203334D
2.5 kg
$2600.00

Gentamicin sulfate, 7.5 kg

sc-203334E
7.5 kg
$6125.00