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Sodium Chloride (CAS 7647-14-5)

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Alternate Names:
Sodium Chloride is also known as table salt.
Application:
Sodium Chloride is used in biochemistry and molecular biology applications as a component of PBS and SSC buffers.
CAS Number:
7647-14-5
Purity:
≥98%
Molecular Weight:
58.44
Molecular Formula:
NaCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium chloride, commonly known as table salt, is an ionic compound with the chemical formula NaCl. It consists of sodium (Na+) and chloride (Cl-) ions, which are held together by ionic bonds. In research, sodium chloride is indispensable due to its role in creating physiological conditions and as a fundamental component in various buffers and media used in biochemical and molecular biology experiments. Its primary mechanism of action in these settings involves maintaining osmotic balance and providing ionic strength, which are crucial for maintaining the stability and activity of biological molecules. For instance, sodium chloride is a key ingredient in saline solutions, where it is used to mimic bodily fluids for cell culture and enzyme assays, ensuring that cells and proteins behave similarly as they would in a living organism. Furthermore, sodium chloride is used in the preparation of buffer solutions for gel electrophoresis of proteins and nucleic acids, helping to maintain the charge and conformation of these molecules during the separation process. Its presence in these buffers ensures that the electrical conductivity is adequate for the migration of biomolecules towards their respective electrodes. Additionally, sodium chloride is employed in the extraction and purification processes of biological samples, where it aids in precipitating proteins and nucleic acids by adjusting the ionic strength of solutions, thereby facilitating easier separation and purification. This wide range of applications highlights sodium chloride′s fundamental role in scientific research, providing essential conditions for experimental consistency and reliability.


Sodium Chloride (CAS 7647-14-5) References

  1. Toxin inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A.  |  Iglewski, BH. and Sadoff, JC. 1979. Methods Enzymol. 60: 780-93. PMID: 111001
  2. Hydrophobic forces between protein molecules in aqueous solutions of concentrated electrolyte.  |  Curtis, RA., et al. 2002. Biophys Chem. 98: 249-65. PMID: 12128178
  3. Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease.  |  Osanai, T., et al. 2002. Blood Purif. 20: 466-8. PMID: 12207094
  4. The influence of particles of a minor component on the matrix strength of sodium chloride.  |  van Veen, B., et al. 2002. Eur J Pharm Sci. 16: 229-35. PMID: 12208452
  5. Sodium chloride deprivation: development of sodium chloride as a reinforcement.  |  WAGMAN, W. 1963. Science. 140: 1403-4. PMID: 13998205
  6. Enhancing effect of sodium chloride on in vitro adsorption of paraquat onto activated carbon.  |  Tanada, S., et al. 1992. Nihon Eiseigaku Zasshi. 46: 1051-6. PMID: 1556828
  7. Isolation of protein kinases from reticulocytes and phosphorylation of initiation factors.  |  Hathaway, GM., et al. 1979. Methods Enzymol. 60: 495-511. PMID: 459914
  8. Role of calcium in the adhesion and fusion of bilayers.  |  Leckband, DE., et al. 1993. Biochemistry. 32: 1127-40. PMID: 8424941
  9. Crystallization of human complement component C5.  |  Discipio, RG., et al. 1998. Acta Crystallogr D Biol Crystallogr. 54: 643-6. PMID: 9761862
  10. Crystallization and preliminary X-ray analysis of ferric enterobactin receptor FepA, an integral membrane protein from Escherichia coli.  |  Smith, BS., et al. 1998. Acta Crystallogr D Biol Crystallogr. 54: 697-9. PMID: 9761879

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium Chloride, 500 g

sc-203274
500 g
$18.00

Sodium Chloride, 2 kg

sc-203274A
2 kg
$23.00

Sodium Chloride, 5 kg

sc-203274B
5 kg
$35.00

Sodium Chloride, 10 kg

sc-203274C
10 kg
$65.00