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Sodium bisulfite, mixture of NaHSO3 and Na2S2O5 (CAS 7631-90-5)

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Alternate Names:
Sodium hydrogensulfite, mixture of NaHSO3 and Na2S2O5
Application:
Sodium bisulfite, mixture of NaHSO3 and Na2S2O5 is an antioxidant and antimicrobial agent for DNA methylation studies
CAS Number:
7631-90-5
Molecular Weight:
104.06
Molecular Formula:
NaHSO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium bisulfite, a mixture of sodium bisulfite (NaHSO3) and sodium metabisulfite (Na2S2O5), is widely recognized for its reducing and antioxidant properties, making it a valuable chemical in various scientific applications. It is extensively used in organic synthesis for the selective reduction of aldehydes and ketones to alcohols, and in biochemical processes to prevent oxidation that could degrade sensitive compounds. One of its key roles in research is in the field of epigenetics, where it facilitates bisulfite sequencing by converting cytosine to uracil, allowing for detailed mapping of DNA methylation patterns—a crucial aspect of gene regulation studies. Additionally, sodium bisulfite is employed in environmental chemistry for the detoxification of heavy metals in waste streams, effectively reducing toxic metals like chromium and mercury to less harmful states. This dual functionality in both advanced genetic research and environmental management underscores its importance and versatility in scientific and industrial sectors.


Sodium bisulfite, mixture of NaHSO3 and Na2S2O5 (CAS 7631-90-5) References

  1. Whole genome amplification of sodium bisulfite-treated DNA allows the accurate estimate of methylated cytosine density in limited DNA resources.  |  Mill, J., et al. 2006. Biotechniques. 41: 603-7. PMID: 17140118
  2. The bisulfite genomic sequencing used in the analysis of epigenetic states, a technique in the emerging environmental genotoxicology research.  |  Hayatsu, H. 2008. Mutat Res. 659: 77-82. PMID: 18485805
  3. Inactivation of glutaraldehyde by reaction with sodium bisulfite.  |  Jordan, SL., et al. 1996. J Toxicol Environ Health. 47: 299-309. PMID: 8604152

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium bisulfite, mixture of NaHSO3 and Na2S2O5, 5 g

sc-203273
5 g
$30.00

Sodium bisulfite, mixture of NaHSO3 and Na2S2O5, 100 g

sc-203273A
100 g
$45.00

Sodium bisulfite, mixture of NaHSO3 and Na2S2O5, 500 g

sc-203273B
500 g
$85.00

Sodium bisulfite, mixture of NaHSO3 and Na2S2O5, 2.5 kg

sc-203273C
2.5 kg
$210.00