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Sarafloxacin hydrochloride (CAS 91296-87-6)

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Application:A fluoroquinolone antibacterial agent
CAS Number:91296-87-6
Purity:≥99%
Molecular Weight:421.9
Molecular Formula:C20H17F2N3O3•HCl
Refer to Certificate of Analysis for lot specific data (including water content).
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Sarafloxacin hydrochloride sc-203255 5 g $52
Sarafloxacin hydrochloride sc-203255A 25 g $170
Description
Sarafloxacin hydrochloride is a fluoroquinolone antibacterial agent. Inhibits bacterial Topo II α (DNA gyrase, topoisomerase). Sarafloxacin hydrochloride is effective against Mycobacterium tuberculosis.
Technical Information
Physical State:Solid
Solubility:Soluble in water (<1 mg/ml at 25 °C), DMSO (1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
Storage:Store at -20° C
Melting Point:>240 °C (dec.)
Boiling Point:621.4 °C at 760 mmHg (Predicted)
Refractive Index:n20D 1.63 (Predicted)
Safety and Reference Information
PubChem CID:56207
Merck Index:14: 8370
MDL Number:MFCD03427297
SMILES:C1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents: D.T. Chu, et al.; J. Med. Chem. 28, 1558 (1985) In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones: P.B. Fernandes, et al.; Antimicrob. Agents Chemother. 29, 201 (1986) In-vitro activity of six fluorinated quinolones against Mycobacterium tuberculosis: O.G. Berlin, et al.; J. Antimicrob. Chemother. 19, 611 (1987) In vitro activities of A-56619 (difloxacin) and A-56620, two aryl fluoroquinolones: A. Digranes & W.L. Dibb; Chemotherapy 34, 298 (1988) Determination of temafloxacin, sarafloxacin, and difloxacin in bulk drug and dosage forms by high-performance liquid chromatography: J.F. Bauer, et al.; Pharm. Res. 7, 1177 (1990)
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