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Antimony (III) Chloride (CAS 10025-91-9)

Application:An apoptosis agent that is used to detect cholesterols and carotenoids.
CAS Number:10025-91-9
Molecular Weight:228.12
Molecular Formula:SbCl3
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Antimony (III) Chloride sc-202955 5 g $39
Antimony (III) Chloride sc-202955A 100 g $81
Antimony (III) Chloride sc-202955B 500 g $289
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Description
Antimony (III) Chloride has been reported to elevate sister chromatid exchange rates in V79 cells after a full day of incubation. This compound has also been noted to cause DNA fragmentation in Chinese hamster ovary cells, as well as a delayed apoptosis. Mechanistic studies suggest that Antimony (III) Chloride increases the calcium accumulation in cells. Antimony (III) Chloride is also used to detect certain compounds, such as cholesterols and carotenoids. This agent seems to cause dehydration of cholesterol to 3,5-cholestadiene and 2,4-cholestadiene which produce the blue color seen during the reaction.
Technical Information
Appearance:White crystalline powder
Physical State:Solid
Storage:Store at 4° C
Safety and Reference Information
Transport:UN 1733, Class 8, Packing group II
RTECS:CC4900000
PubChem CID:24814
Merck Index:14: 707
MDL Number:MFCD00011212
EC Number:233-047-2
SMILES:Cl[Sb](Cl)Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Kurasawa, Y., et al. 1978. Steroids. 31: 163-174. PMID: 663961
2. Gurnani, N., et al. 1992. Cytobios. 70: 131-136. PMID: 1451533
3. Huang, H., et al. 1998. Toxicology. 129: 113-123. PMID: 9772090
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