Ansatrienin B (CAS 82189-04-6)

Application:	An ansamycin antibiotic that contains a triene structure
CAS Number:	82189-04-6
Molecular Weight:	638.8
Molecular Formula:	C₃₆H₅₀N₂O₈

Description

Ansatrienin B is an ansamycin antibiotic isolated from Streptomyces rishiriensis, and contains a triene structure. It displays antitumor antibiotic activity, potentiating significantly the action of many clinical antitumor agents. It also displays potent anticancer activities. Ansatrienin B has been reported to inhibit parathyroid hormone-stimulated bone resorption in a concentration-dependent manner.

Technical Information

Appearance:	Yellow powder
Physical State:	Solid
Solubility:	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
Storage:	Store at -20° C

Safety and Reference Information

PubChem CID:	6440888
SMILES:	C[C@@H]1[C@H](C/C=C/C=C/C=C/[C@@H](CC(=O)NC2=C(C(=CC(=C2)O)CC/C=C(/[C@@ H]1O )\C)O)OC)OC(=O)[C@@H](C)NC(=O)C3CCCCC3

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Coronelli, C., et al. 1967. J. Antibiot. 20: 329-333. PMID: 5631366
2. Kuwano, M., et al. 1983. Gann. 74: 759-766. PMID: 6196249
3. Feuerbach, D., et al. 1995. J. Biol. Chem. 270: 25949-25955. PMID: 7592784

SDS

Datasheet/SDS