Welcome to Santa Cruz Biotechnology!

Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt (CAS 94825-44-2)

(Based on popularity)

Application:A G-protein-activating GTP analog
CAS Number:94825-44-2
Molecular Weight:562.98
Molecular Formula:C10H12LI4N5O13P3S
Refer to Certificate of Analysis for lot specific data (including water content).
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt sc-202639 10 mg $278
Description
Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt is a Gβ-activating (G-protein-activating) GTP analog, which is more resistant to hydrolysis than GTP. Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt induces exocytosis in isolated mouse pancreatic acinar cells. Also reported to stimulate insulin release from pancreatic β-cells.
Technical Information
Appearance:Powder
Physical State:Solid
Solubility:Soluble in water (≥75 mg/ml).
Storage:Store at -20° C
Refractive Index:n20D 1.95 (Predicted)
Ki Data:Kappa opioid receptor: Ki= 0.0048 nM (human)
pK Values:pKa: 0.97 (Predicted), pKb: 2.42 (Predicted)
Safety and Reference Information
WGK Germany:3
PubChem CID:44134755
MDL Number:MFCD00135151
EC Number:305-606-1
Beilstein Registry:8182249
SMILES:[Li+].[Li+].[Li+].[Li+].NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(= O)OP([O-])([O-])=S)[C@@H](O)[C@H]2O)C(=O)N1
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1.Lino, S., et al. 2000. FEBS Lett. 479, 46. 2.Martelli, A.M., et al. 1996. Biochem. Biophys. Res. Commun. 218, 182. 3.Hess, S.D., et al. 1993. Science 259, 1169. 4.Ekstrom, R.C., et al. 1992. J. Biol. Chem. 267, 22183. 5.McGuirk, S.M., and Dolphin, A.C. 1992. Neurosci. 49, 117. Vaca, L., et al. 1992. Eur. J. Physiol. 422, 66. 6.Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466. 7.Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615. 8.Orellana, S., et al. 1987. J. Biol. Chem.. 262, 1638.
SDS (MSDS)
Certificate of Analysis

Catalog Number

Lot Number

Related Product Categories