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DPPH, Free Radical (CAS 1898-66-4)

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Synonym:1,1-Diphenyl-2-picrylhydrazyl radical; 2,2-Diphenyl-1-picrylhydrazyl (free radical)
Application:A sensitive colormetric free radical scavenger
CAS Number:1898-66-4
Purity:>90%
Molecular Weight:394.32
Molecular Formula:C18H12N5O6
Refer to Certificate of Analysis for lot specific data (including water content).
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DPPH, Free Radical sc-202591 50 mg $40
Description
DPPH, Free Radical is a cell-permeable, stable free radical that acts as a hydrogen radical scavenger. Originally developed to detect melanin metabolites in the urine of subjects with malignant melanoma, it has found numerous applications as a general antioxidant detector. Useful in inducing free-radical injury to tissues and as a screening tool for detecting free radical scavenging activity of antioxidants. The ability of a compound to decolorize DPPH free radical signifies the reactivity of the tested compound. Used in the quantitative determination of aliphatic and aromatic thiols by indirect spectroscopy and for photometric determination of tocopherol.
Technical Information
Physical State:Solid
Solubility:Soluble in DMF, EtOH, chloroform, ether, carbon disulfinde, acetone, oils, carbon tetrachloride, glacial acetis acid, and toluene. Insoluble in water.
Storage:Store at -20° C
Melting Point:~135 °C (lit.)(dec.)
Safety and Reference Information
WGK Germany:1
PubChem CID:2735032
Merck Index:14: 3330
MDL Number:MFCD00007231
EC Number:217-591-8
Beilstein Registry:1846081
SMILES:C1=CC=C(C=C1)N(C2=CC=CC=C2)[N]C3=C(C=C(C=C3[N+](=O)[O-])[N+](=O)[O-])[N+](=O )[O-]
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Banda, P.W., et al. 1974. Anal. Chem. 46: 1772-1777. PMID: 4411963
2. Dinis, T.C., et al. 1994. Arch. Biochem. Biophys. 315: 161-169. PMID: 7979394
3. Ancerewicz, J., et al. 1998. Free Radic. Biol. Med. 25: 113-120. PMID: 9655529
4. Karki, S.B., et al. 2000. J Pharm Sci. 89: 1518-1524. PMID: 11042599
5. Weber, V., et al. 2001. Arzneimittelforschung. 51: 877-884. PMID: 11765588
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