Date published: 2025-10-17

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1-Aminocyclopropane-1-carboxylic Acid (CAS 22059-21-8)

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Alternate Names:
1-Aminocyclopropanecarboxylic Acid; 1-Amino-1-carboxycyclopropane; 1-Aminocyclopropane-1-carboxylate
Application:
1-Aminocyclopropane-1-carboxylic Acid is an agonist at the NMDA receptor glycine modulatory site
CAS Number:
22059-21-8
Purity:
≥98%
Molecular Weight:
101.11
Molecular Formula:
C4H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Aminocyclopropane-1-carboxylic Acid is a compound of significant interest in plant physiology and biochemistry research. It serves as a precursor to ethylene, a gaseous plant hormone that plays a critical role in the regulation of plant growth and development. Studies involving 1-Aminocyclopropane-1-carboxylic Acid focus on its biosynthesis and conversion to ethylene, particularly in relation to fruit ripening, senescence, and stress responses in plants. Researchers also examine the enzymatic pathways that convert ACC to ethylene, including the role of ACC oxidase and its expression under various physiological conditions. Furthermore, 1-Aminocyclopropane-1-carboxylic Acid is used in the study of signal transduction pathways that mediate plant responses to environmental stimuli.


1-Aminocyclopropane-1-carboxylic Acid (CAS 22059-21-8) References

  1. Synthesis and degradation of 1-aminocyclopropane-1-carboxylic acid by Penicillium citrinum.  |  Jia, YJ., et al. 1999. Biosci Biotechnol Biochem. 63: 542-9. PMID: 10227140
  2. The regulation of 1-aminocyclopropane-1-carboxylic acid synthase gene expression during the transition from system-1 to system-2 ethylene synthesis in tomato.  |  Barry, CS., et al. 2000. Plant Physiol. 123: 979-86. PMID: 10889246
  3. Ethylene biosynthesis: Identification of 1-aminocyclopropane-1-carboxylic acid as an intermediate in the conversion of methionine to ethylene.  |  Adams, DO. and Yang, SF. 1979. Proc Natl Acad Sci U S A. 76: 170-4. PMID: 16592605
  4. 1-aminocyclopropane-1-carboxylate synthase in tomato is encoded by a multigene family whose transcription is induced during fruit and floral senescence.  |  Rottmann, WH., et al. 1991. J Mol Biol. 222: 937-61. PMID: 1762159
  5. 1-Aminocyclopropane carboxylic acid: a potent and selective ligand for the glycine modulatory site of the N-methyl-D-aspartate receptor complex.  |  Marvizón, JC., et al. 1989. J Neurochem. 52: 992-4. PMID: 2465385
  6. 1-Aminocyclopropane-1-carboxylic acid (ACC) mimics the effects of glycine on the NMDA receptor ion channel.  |  Nadler, V., et al. 1988. Eur J Pharmacol. 157: 115-6. PMID: 2466672
  7. 1-aminocyclopropane-1-carboxylic acid (ACC) in plants: more than just the precursor of ethylene!  |  Van de Poel, B. and Van Der Straeten, D. 2014. Front Plant Sci. 5: 640. PMID: 25426135
  8. Blockade of N-methyl-D-aspartate induced convulsions by 1-aminocyclopropanecarboxylates.  |  Skolnick, P., et al. 1989. Life Sci. 45: 1647-55. PMID: 2685487
  9. 1-Aminocyclopropane-1-Carboxylic Acid Oxidase (ACO): The Enzyme That Makes the Plant Hormone Ethylene.  |  Houben, M. and Van de Poel, B. 2019. Front Plant Sci. 10: 695. PMID: 31191592
  10. 1-Aminocyclopropane carboxylic acid (ACPC) prevents mu and delta opioid tolerance.  |  Kolesnikov, YA., et al. 1994. Life Sci. 55: 1393-8. PMID: 7934650
  11. 1-Aminocyclopropane-carboxylic acid reduces NMDA-induced hippocampal neurodegeneration in vivo.  |  Zapata, A., et al. 1996. Neuroreport. 7: 397-400. PMID: 8730790
  12. Glycine site antagonists and partial agonists inhibit N-methyl-D-aspartate receptor-mediated [3H]arachidonic acid release in cerebellar granule cells.  |  Viu, E., et al. 1998. J Pharmacol Exp Ther. 285: 527-32. PMID: 9580593
  13. Two Arabidopsis mutants that overproduce ethylene are affected in the posttranscriptional regulation of 1-aminocyclopropane-1-carboxylic acid synthase.  |  Woeste, KE., et al. 1999. Plant Physiol. 119: 521-30. PMID: 9952448

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Aminocyclopropane-1-carboxylic Acid, 500 mg

sc-202393
500 mg
$140.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-3508, is provided as a white to off-white crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-17
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Rated 5 out of 5 by from Excellent productI bought this product about a year ago and used it to determine bacterial ACC deaminase activity. I can say it is a quality product at a very cheap.
Date published: 2017-11-06
Rated 5 out of 5 by from LizadaLizada, et al. (PubMed ID 543532) developed a simple and sensitive test for quantitation of 1-Aminocyclopropane-1-carboxylic Acid, also known as ACC. This method can detect ACC in amounts as small as 5pmoles. -SCBT Publication Review
Date published: 2015-02-19
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1-Aminocyclopropane-1-carboxylic Acid is rated 5.0 out of 5 by 2.
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