Date published: 2026-4-15

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Prodigiosin (CAS 82-89-3)

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Alternate Names:
Prodigiosine; 4-Methoxy-5-[(5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl]-2,2-bi[1H-pyrrole]
Application:
Prodigiosin is a potent proapoptotic compound that also acts as an antibiotic
CAS Number:
82-89-3
Purity:
>95%
Molecular Weight:
323.43
Molecular Formula:
C20H25N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Prodigiosin is a red pigment found in certain strains of bacteria, including Serratia marcescens, and is of interest in various research areas due to its distinctive properties. In microbiological research, prodigiosin is often used as a model to study pigment biosynthesis and regulation within bacterial cells. Its biosynthetic pathway involves a series of enzymatic reactions that are useful for understanding the genetic and environmental factors affecting secondary metabolite production in microorganisms. In environmental science, prodigiosin serves as a marker for monitoring the presence and activity of pigment-producing bacteria in different habitats. In material science, researchers explore the potential of prodigiosin as a natural dye for fabrics and its application in the development of sensing materials due to its colorimetric changes under different conditions. Additionally, the compound is studied for its role in bacterial signaling and survival, contributing to the broader understanding of microbial ecology and interactions.


Prodigiosin (CAS 82-89-3) References

  1. Prodigiosin-induced apoptosis in human colon cancer cells.  |  Montaner, B. and Pérez-Tomás, R. 2001. Life Sci. 68: 2025-36. PMID: 11388704
  2. Prodigiosin induces apoptosis of B and T cells from B-cell chronic lymphocytic leukemia.  |  Campàs, C., et al. 2003. Leukemia. 17: 746-50. PMID: 12682632
  3. A novel medium for the enhanced cell growth and production of prodigiosin from Serratia marcescens isolated from soil.  |  Giri, AV., et al. 2004. BMC Microbiol. 4: 11. PMID: 15113456
  4. Antimetastatic effect of prodigiosin through inhibition of tumor invasion.  |  Zhang, J., et al. 2005. Biochem Pharmacol. 69: 407-14. PMID: 15652232
  5. The Antibiotic Activity of Violacein, Prodigiosin, and Phthiocol.  |  Lichstein, HC. and Van De Sand, VF. 1946. J Bacteriol. 52: 145-6. PMID: 16561146
  6. The anticancer agent prodigiosin induces p21WAF1/CIP1 expression via transforming growth factor-beta receptor pathway.  |  Soto-Cerrato, V., et al. 2007. Biochem Pharmacol. 74: 1340-9. PMID: 17765876
  7. Prodigiosins: a novel family of immunosuppressants with anti-cancer activity.  |  Pandey, R., et al. 2007. Indian J Biochem Biophys. 44: 295-302. PMID: 18341204
  8. Prodigiosin down-regulates survivin to facilitate paclitaxel sensitization in human breast carcinoma cell lines.  |  Ho, TF., et al. 2009. Toxicol Appl Pharmacol. 235: 253-60. PMID: 19133282
  9. Cyclic AMP negatively regulates prodigiosin production by Serratia marcescens.  |  Kalivoda, EJ., et al. 2010. Res Microbiol. 161: 158-67. PMID: 20045458
  10. The RssB/RssA two-component system regulates biosynthesis of the tripyrrole antibiotic, prodigiosin, in Serratia marcescens.  |  Horng, YT., et al. 2010. Int J Med Microbiol. 300: 304-12. PMID: 20347390
  11. Apoptosis of human lung adenocarcinoma A549 cells induced by prodigiosin analogue obtained from an entomopathogenic bacterium Serratia marcescens.  |  Zhou, W., et al. 2010. Appl Microbiol Biotechnol. 88: 1269-75. PMID: 20717667
  12. Prodigiosin production by Serratia marcescens UCP 1549 using renewable-resources as a low cost substrate.  |  de Araújo, HW., et al. 2010. Molecules. 15: 6931-40. PMID: 20938403
  13. High-level production of microbial prodigiosin: A review.  |  Han, R., et al. 2021. J Basic Microbiol. 61: 506-523. PMID: 33955034

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prodigiosin, 500 µg

sc-202298
500 µg
$369.00

Prodigiosin, 2.5 mg

sc-202298A
2.5 mg
$1274.00