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N⁹-Isopropyl-olomoucine (CAS 158982-15-1)

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Application:	An inhibitor of CDK1/cyclin B and CDK5/p35
CAS Number:	158982-15-1
Purity:	≥98%
Molecular Weight:	326.4
Molecular Formula:	C₁₇H₂₂N₆O

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
N⁹-Isopropyl-olomoucine	sc-202264	1 mg	$30
N⁹-Isopropyl-olomoucine	sc-202264A	5 mg	$85

Description

N⁹-Isopropyl-olomoucine is an inhibitor of CDK1/cyclin B (IC₅₀ = 2 µM) and CDK5/p35 (IC₅₀ = 3 µM).

Technical Information

Appearance:	White to off-white crystalline
Physical State:	Solid
Solubility:	Soluble in DMSO or dimethyl formamide; sparingly soluble in methanol.
Storage:	Store at -20° C

Safety and Reference Information

PubChem CID:	6610355
MDL Number:	MFCD01310377
SMILES:	CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Vesely, J., et al. 1994. Eur. J. Biochem. 224: 771-786. PMID: 7925396
2. Raynaud, F.I., et al. 2004. Mol. Cancer Ther. 3: 353-362. PMID: 15026556

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