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PDI (H-160) Antibody: sc-20132

 |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 211-370 mapping to an internal region of PDI (protein disulfide isomerase) of human origin
  • recommended for detection of PDI of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
  • agarose conjugate for IP studies, sc-20132 AC, 500 µg/0.25 ml agarose
 
Additional PDI Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human P4HB 5034 17q25.3 NM_000918 P07237
176790
Mouse P4hb 18453 11 E2 P09103
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PDI (H-160) sc-20132 200 µg/ml $279
PDI (H-160) AC sc-20132 AC 500µg/ml, 25%ag $366
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PDI siRNA (h) sc-36201 10 µM $258
PDI siRNA (m) sc-36202 10 µM $258
PDI siRNA (h2) sc-44319 10 µM $258
PDI (h)-PR sc-36201-PR 10 µM $23
PDI (m)-PR sc-36202-PR 10 µM $23
PDI (h2)-PR sc-44319-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PDI shRNA Plasmid (h) sc-36201-SH 20 µg $520
PDI shRNA Plasmid (m) sc-36202-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PDI shRNA (h) Lentiviral Particles sc-36201-V 200 µl $625
PDI shRNA (m) Lentiviral Particles sc-36202-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
COLO 320DM Cell Lysate sc-2226 500 µg/200 µl $104
mouse liver extract sc-2256 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
rat liver extract sc-2395 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
PDI (h2): 293T Lysate sc-113640 100µg/200µl $205
PDI (h): 293 Lysate sc-111237 100µg/200µl $205

PDI Background Information
Oxidoreductase-protein disulfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disulfide exchange, mediates folding of newly synthesized proteins and functions as a molecular chaperone. PDI localizes to the lumen of the endoplasmic reticulum (ER), where in conjunction with folding-helper proteins, such as immunoglobulin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sulfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regulating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.

PDI (H-160) Product Citations
See how others have used PDI (H-160): sc-20132 antibody and or PDI (H-160) antibody conjugates.


13 total citations
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PDI (H-160)
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PDI (H-160): sc-20132. Western blot analysis of PDI expression in COLO 320DM (A) and Hep G2 (B) whole cell lysates.
PDI (H-160): sc-20132. Immunofluorescence staining of methanol-fixed Hep G2 cells showing cytoplasmic localization.
PDI (H-160): sc-20132. Western blot analysis of PDI expression in A-431 whole cell lysate.
PDI (H-160): sc-20132. Western blot analysis of PDI expression in non-transfected 293T: sc-117752 (A), human PDI transfected 293T: sc-113640 (B) and Hep G2 (C) whole cell lysates
PDI (H-160): sc-20132. Western blot analysis of PDI expression in non-transfected 293T: sc-117752 (A), human PDI transfected 293T: sc-111237 (B) and Hep G2 (C) whole cell lysates.
PDI (H-160): sc-20132. Western blot analysis of PDI expression in non-transfected: sc-117752 (A) and mouse PDI transfected: sc-125796 (B) 293T whole cell lysates.
PDI (H-160): sc-20132. Western blot analysis of PDI expression in non-transfected 293: sc-110760 (A), human PDI transfected 293: sc-158832 (B) and Hep G2 (C) whole cell lysates.
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