U-37883A (CAS 57568-80-6)

Application:	A potent inhibitor of vascular smooth muscle KIR6 channels
CAS Number:	57568-80-6
Molecular Weight:	381.98
Molecular Formula:	C₂₁H₃₅N₃O·HCl

Ordering Information

Product Name	Catalog #	Unit	Price	Qty	Add
U-37883A	sc-201001	5 mg	$75
U-37883A	sc-201001A	25 mg	$299

Description

U-37883A is a potent inhibitor of vascular smooth muscle K-ATP (KIR6) channels. Useful biological tool in distinguishing between Kir6.1 and Kir6.2 chimeric protein functions as well as the different sulfonylurea-sensitive K+ channel subtypes. This product shows

Technical Information

Appearance:	White
Physical State:	Solid
Solubility:	Soluble in water(5 mg/ml)
Storage:	Store at room temperature

Safety and Reference Information

PubChem CID:	64392
SMILES:	C1CCC(CC1)N=C(NC23CC4CC(C2)CC(C4)C3)N5CCOCC5.Cl

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

References

1. Lin, Y.J., et al. 1998. Eur. J. Pharmacol. 352: 335-341. PMID: 9716371
2. Wellman, G.C., et al. 1999. Br. J. Pharmacol. 128: 909-916. PMID: 10556925
3. Kovalev, H., et al. 2004. Br. J. Pharmacol. 141: 867-873. PMID: 14757705
4. Teramoto, N. 2006. Cardiovasc Drug Rev. 24: 25-32. PMID: 16939631
5. Ploug, K.B., et al. 2008. Br. J. Pharmacol. 154: 72-81. PMID: 18332850

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