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Eicosa-11Z,14Z-dienoic Acid (CAS 2091-39-6)

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Synonym:cis-11,14-Eicosadienoic acid
Application:A polyunsaturated lipid analog of arachidonic acid that inhibits calcineurin
CAS Number:2091-39-6
Molecular Weight:308.50
Molecular Formula:C20H36O2
Refer to Certificate of Analysis for lot specific data (including water content).
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Product NameCatalog #UnitPriceQtyAddFavorites
Eicosa-11Z,14Z-dienoic Acid sc-200776 100 mg $30
Eicosa-11Z,14Z-dienoic Acid sc-200776A 1 g $159
Description
Eicosa-11Z,14Z-dienoic acid is a polyunsaturated lipid analog of arachidonic acid. It has been shown to inhibit PP2 (calcineurin), a protein phosphatase which activates immune system T cells, to some extent in the absence of calmodulin.
Technical Information
Appearance:Oil
Physical State:Liquid
Solubility:Soluble in ethanol (~100 mg/ml), DMSO (~100 mg/ml), and DMF (~100 mg/ml). Insoluble in water.
Storage:Store at -20° C
Boiling Point:198 °C at 0.08 mmHg
Refractive Index:n20D 1.48
Ki Data:binding of [3H]-LTB4 to neutrophil membranes: Ki= 3 µM (pig)
Safety and Reference Information
WGK Germany:3
PubChem CID:6439848
MDL Number:MFCD00673431
SMILES:CCCCC/C=CC/C=CCCCCCCCCCC(=O)O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
References
1. Tokheim, A.M., et al. 2006. Bioorg. Chem. 34: 66-76. PMID: 16464485
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