Molecular structure of CP-55,940, CAS Number: 83002-04-4
CP-55,940 (CAS 83002-04-4)
See product citations (4)
Alternate Names:
CP-55,940 also known as 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol; CP-55940; CP55940; 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol; 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl) cyclohexyl]-5-(2-methyloctan-2-yl)phenol
Application:
CP-55,940 is a cannabimimetic small molecule and potent non-selective cannabinoid receptor agonist
CAS Number:
83002-04-4
Purity:
≥96%
Molecular Weight:
376.6
Molecular Formula:
C24H40O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
CP-55,940 is a cannabimimetic small molecule and a potent cannabinoid receptor agonist, demonstrating similar binding activity at both receptor types (CB1 Ki=0.58 nM, CB2 Ki=0.69 nM). CP-55,940 represents a useful non-selective agonist entry into the growing library of synthetic cannabimimetics, compounds which are being actively explored for efficacy in perturbing Alzheimer′s disease and other neurodegenerative states.
CP-55,940 (CAS 83002-04-4) References
- Intracerebral self-administration of the cannabinoid receptor agonist CP 55,940 in the rat: interaction with the opioid system. | Braida, D., et al. 2001. Eur J Pharmacol. 413: 227-34. PMID: 11226397
- Antinociceptive, behavioural and neuroendocrine effects of CP 55,940 in young rats. | Romero, EM., et al. 2002. Brain Res Dev Brain Res. 136: 85-92. PMID: 12101025
- Involvement of the kappa-opioid receptor in the anxiogenic-like effect of CP 55,940 in male rats. | Marín, S., et al. 2003. Pharmacol Biochem Behav. 74: 649-56. PMID: 12543231
- Chronic treatment with CP 55,940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood. | Biscaia, M., et al. 2003. Psychopharmacology (Berl). 170: 301-308. PMID: 12955302
- Involvement of 5-HT1A receptors in behavioural effects of the cannabinoid receptor agonist CP 55,940 in male rats. | Marco, EM., et al. 2004. Behav Pharmacol. 15: 21-7. PMID: 15075623
- Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice. | Gilbert, MT., et al. 2016. Neurotoxicol Teratol. 58: 15-22. PMID: 26708672
- Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats. | Wiley, JL., et al. 1995. Neuropharmacology. 34: 669-76. PMID: 7566504
- Chronic CP-55,940 alters cannabinoid receptor mRNA in the rat brain: an in situ hybridization study. | Rubino, T., et al. 1994. Neuroreport. 5: 2493-6. PMID: 7696588
- Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain. | Rinaldi-Carmona, M., et al. 1996. Life Sci. 58: 1239-47. PMID: 8614277
- Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice. | Fan, F., et al. 1996. Brain Res. 706: 13-20. PMID: 8720487
- Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. | Showalter, VM., et al. 1996. J Pharmacol Exp Ther. 278: 989-99. PMID: 8819477
- Aversive effects of the synthetic cannabinoid CP 55,940 in rats. | McGregor, IS., et al. 1996. Pharmacol Biochem Behav. 53: 657-64. PMID: 8866969
- Comparative receptor binding analyses of cannabinoid agonists and antagonists. | Thomas, BF., et al. 1998. J Pharmacol Exp Ther. 285: 285-92. PMID: 9536023
Activator of:
CB1, and CB2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CP-55,940, 5 mg | sc-200359 | 5 mg | $185.00 | |||
CP-55,940, 25 mg | sc-200359A | 25 mg | $850.00 |