CD58 Background Information CD2 (also designated E-rosette receptor) interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/ CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on T lymphocytes, NK cells and thymocytes, as well as on mouse B cells and rat splenic macrophages. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium.
CD58 (TS2/9.1.4.3) Product Citations
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CD58 (TS2/9.1.4.3)
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CD58 (TS2/9.1.4.3): sc-20009. Western blot analysis of CD58 expression in CCRF-CEM (A) and Raji (B) whole cell lysates.
CD58 (TS2/9.1.4.3): sc-20009. Indirect FCM analysis of Jurkat cells stained with CD58 (TS2/9.1.4.3), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877.
CD58 (TS2/9.1.4.3) PE: sc-20009 PE. FCM analysis of Jurkat cells. Black line histogram represents the isotype control, normal mouse IgG1: sc-2866.