santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Lymphocyte Signaling » CD83 Antibody / CD83 Antibodies » CD83 (HB15a): sc-19677

CD83 (HB15a) Antibody: sc-19677

  |  Datasheet
  • mouse monoclonal IgG2b; 200 µg/ml
  • raised against COS cells transfected with HB15 cDNA
  • recommended for detection of CD83 of human origin by WB, IP, IF, IHC(P) and FCM
  • fluorescein (sc-19677 FITC) and phycoerythrin (sc-19677 PE) conjugates for FCM, 100 tests
  • also provided azide-free for activation, sc-19677 L, 200 µg/0.1 ml
 
Additional CD83 Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CD83 9308 6p23 NM_001040280, NM_004233 Q01151
 604534
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CD83 (HB15a) sc-19677 200 µg/ml $279
CD83 (HB15a) FITC sc-19677 FITC 100 tests in 2 ml $292
CD83 (HB15a) L sc-19677 L 200 µg/0.1 ml $279
CD83 (HB15a) PE sc-19677 PE 100 tests in 2ml $303
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD83 siRNA (h) sc-42808 10 µM $258
CD83 (h)-PR sc-42808-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD83 shRNA Plasmid (h) sc-42808-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CD83 shRNA (h) Lentiviral Particles sc-42808-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
Ramos Cell Lysate sc-2216 500 µg/200 µl $104
CCRF-CEM Cell Lysate sc-2225 500 µg/200 µl $104
MOLT-4 Cell Lysate sc-2233 500 µg/200 µl $104

CD83 Background Information
CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anti-cancer vaccine. CD83-IgG1(fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like Lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting dendritic cell interactions with monocytes and CD8+ T cells.

CD83 (HB15a) Product Citations
See how others have used CD83 (HB15a): sc-19677 antibody and or CD83 (HB15a) antibody conjugates.


5 total citations
Loading citations.
 
CD83 (HB15a)
Click on image to enlarge
sc-19677
CD83 (HB15a): sc-19677. Immunofluorescence staining of methanol-fixed Ramos cells showing membrane localization.
sc-19677
CD83 (HB15a) PE: sc-19677 PE. FCM analysis of K-562-human CD83 stable transfectant cell line (solid orange histogram) and non-transfected K-562 (dotted green histogram) cells. Black line histogram represents the isotype control, normal mouse IgG2b, sc-2868. Transfected cell line kindly provided by Dr. Thomas Tedder at Duke University Medical Center.
sc-19677
CD83 (HB15a): sc-19677. Western blot analysis of CD83 expression in K-562 whole cell lysate.
Download
Datasheets
Get Adobe Acrobat Reader