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pan ECA (MECA-32) Antibody: sc-19603 |
| Datasheet |
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- rat monoclonal IgG2a; 200 µg/ml
- raised against mouse lymph node stromal cells
- recommended for detection of a dimer of subunits expressed on endothelial cells in embryonic and adult mouse, with the exception of cardiac muscle, skeletal muscle and brain by IP, IF and FCM
- fluorescein (sc-19603 FITC) and phycoerythrin (sc-19603 PE) conjugates for FCM, 100 tests
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Ordering Information
Recommended Support Products:
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Mouse |
Plvap |
84094 |
8 B3.3 |
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Q91VC4
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N/A |
| Mouse |
Plvap |
84094 |
8 B3.3 |
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Q91VC4
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N/A |
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pan ECA Background Information
The vascular network is a highly branched closed circuit of blood vessels, which extends throughout the body and mediates the delivery and exchange of blood. Blood vessels consist of an endothelium, which is a continuous, cylindrical epithelial cell layer, a basal lamina, and an outer mural cell layer. In addition to blood vessels, endothelial cells line the interiors of tissue cavities and spaces. MECA-32 is a mouse monoclonal antibody that shows high specificity for mouse endothelium in both embryonic and mature tissues. The MECA-32 antigen is expressed on most endothelial cells of the embryonic and adult mouse, with the exception of brain, skeletal, and cardiac muscle. In skeletal and cardiac muscle, small arterioles and venules express the MECA-32 antigen. In the brain, MECA-32 expression negatively correlates with the differentiation of the vasculature to form the blood brain barrier. |
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pan ECA (MECA-32)
Click on image to enlarge
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pan ECA (MECA-32) PE: sc-19603 PE. FCM analysis of TK-1 cells. Black line histogram represents the isotype control, normal rat IgG 2a: sc-2872. |
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