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home » Membrane Receptors » VLDLR Antibody / VLDLR Antibodies » VLDLR (6A6): sc-18824

VLDLR (6A6) Antibody: sc-18824

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against a C-terminus 10 amino acid peptide corresponding to VLDL receptor of rat origin
  • recommended for detection of VLDLR of mouse, rat and human origin by WB, IP, IF and IHC(P)
 
Additional VLDLR Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human VLDLR 7436 9p24.2 NM_001018056, NM_003383 P98155
 224050
Mouse Vldlr 22359 19 C1 P98156
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
VLDLR (6A6) sc-18824 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
VLDLR siRNA (h) sc-36822 10 µM $258
VLDLR siRNA (m) sc-36823 10 µM $258
VLDLR (h)-PR sc-36822-PR 10 µM $23
VLDLR (m)-PR sc-36823-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
VLDLR shRNA Plasmid (h) sc-36822-SH 20 µg $520
VLDLR shRNA Plasmid (m) sc-36823-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
VLDLR shRNA (h) Lentiviral Particles sc-36822-V 200 µl $625
VLDLR shRNA (m) Lentiviral Particles sc-36823-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-10 Cell Lysate sc-3806 500 µg/200 µl $104
VLDLR (m): 293T Lysate sc-124572 100µg/200µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

VLDLR Background Information
VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, Megalin, VLDLR and ApoER2 (1). The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain (2). VLDLR is expressed in brain, heart, skeletal muscle and adipose tissue (1,3). It associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR (4,5). VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase (1,6). This pathway regulates the migration of neurons along the radial glial fiber network during brain development (1,6,7).

VLDLR (6A6) Product Citations
See how others have used VLDLR (6A6): sc-18824 antibody and or VLDLR (6A6) antibody conjugates.


8 total citations
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VLDLR (6A6)
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sc-18824
VLDLR (6A6): sc-18824. Western blot analysis of VLDLR expression in HeLa (A) and A-10 (B) whole cell lysates.
sc-18824
VLDLR (6A6): sc-18824. Immunofluorescence staining of methanol-fixed A-10 cells showing cytoplasmic staining.
sc-18824
VLDLR (6A6): sc-18824. Western blot analysis of VLDLR expression in non-transfected: sc-117752 (A) and mouse VLDLR transfected: sc-124572 (B) 293T whole cell lysates.
sc-18824
VLDLR (6A6): sc-18824. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells & islet cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-18824
VLDLR (6A6): sc-18824. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells & islet cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
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