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p-PKC δ Antibody (Tyr 525): sc-18368

 |  Datasheet

(Based on data analysis)
  • p-PKC δ Antibody (Tyr 525) is a goat polyclonal IgG provided at 200 µg/ml; also available as rabbit IgG provided at 200 µg/ml, sc-18368-R
  • recommended for detection of Tyr 525 phosphorylated PKC δ of human origin by WB and IF; also reactive with additional species, including avian
  • blocking peptide, sc-18368 P
 

See additional PKC Antibodies including PKC, PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC eta, PKC gamma, PKC iota, PKC lambda, PKC mu, PKC nu, PKC theta, PKC zeta and Pkc1.

Also see PKC delta Inhibitors or PKC delta Substrates for functional analysis of cellular responses to PKC delta.


Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-PKC δ Antibody (Tyr 525) sc-18368 200 µg/ml $279
p-PKC δ (Tyr 525) P sc-18368 P
(peptide)
 100 µg/0.5 ml $61
p-PKC δ Antibody (Tyr 525)-R sc-18368-R 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC δ siRNA (h) sc-36253 10 µM $258
PKC δ siRNA (h2) sc-44229 10 µM $258
PKC δ (h)-PR sc-36253-PR 10 µM, 20 µl $23
PKC δ (h2)-PR sc-44229-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC δ shRNA Plasmid (h) sc-36253-SH 20 µg $520
PKC δ shRNA Plasmid (h2) sc-44229-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC δ shRNA (h) Lentiviral Particles sc-36253-V 200 µl $625
PKC δ shRNA (h2) Lentiviral Particles sc-44229-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa + PMA Cell Lysate sc-2258 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRKCD 5580 3p21.1 NM_006254, NM_212539 Q05655
 176977
 

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function (1,2). PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids (3). Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC (4,5). PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (å, ∫I, ∫II and ©) and novel (n) PKC isoforms (∂, é , Ω, h and †) (6). PKC isoforms can be activated through tyrosine phosphorylation and catalytically activated upon treatment with H2O2 (7,8). The Tyr 155, 525, 523 and 565 residues in the catalytic domain are crucial for activation of these enzymes (7,8). The residue Ser 643 appears to be an autophosphorylation site (9).