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osteocalcin (M-15) Antibody: sc-18322 |
| Datasheet |
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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of osteocalcin of mouse origin
- recommended for detection of osteocalcin proteins OG1, OG2 and ORG of mouse origin by WB, IP, IF and ELISA
- blocking peptide, sc-18322 P
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Mouse |
Bglap1 |
12096 |
3 F1 |
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NP_001033028
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N/A |
| Mouse |
Bglap2 |
12097 |
3 F1 |
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P04641
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N/A |
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osteocalcin Background Information
Bone g-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. In addition, osteocalcin is one of the most abundant, non-collagenous proteins found in mineralized adult bone. Genetic variation at the osteocalcin locus on chromosome 1q impacts postmenopause bone mineral density (BMD) levels and may predispose some women to osteoporosis.
| osteocalcin (M-15) Product Citations |
See how others have used osteocalcin (M-15): sc-18322 antibody and or osteocalcin (M-15) antibody conjugates.
5 total citations Loading citations.
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osteocalcin (M-15)
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osteocalcin (M-15): sc-18322. Western blot analysis of mouse recombinant osteocalcin.
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