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EMBP Antibody (S-20): sc-18241

 |  Datasheet

(Based on data analysis)

  • EMBP Antibody (S-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of EMBP of mouse origin
  • recommended for detection of EMBP of mouse and rat origin by WB, IF and ELISA
  • blocking epitope, sc-18241 P

See additional EMBP Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP Antibody (S-20) sc-18241 200 µg/ml $279
EMBP (S-20) P sc-18241 P
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP siRNA (m) sc-42905 10 µM $258
EMBP (m)-PR sc-42905-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP shRNA Plasmid (m) sc-42905-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
EMBP shRNA (m) Lentiviral Particles sc-42905-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
RAW 264.7 Whole Cell Lysate sc-2211 500 µg/200 µl $104
mouse spleen extract sc-2391 500 µg/200 µl $104
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Prg2 19074 2 D Q61878

The eosinophil major basic protein (EMBP), also designated MBP, PRG2, proteoglycan 2, BMPG, or bone marrow natural killer cell activator, is a constituent of the crystalline core of the eosinophil granule. High levels of the pro-EMBP are present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT) and C3dg. EMBP may influence antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and may play a role in immune hypersensitivity reactions. EMBP stimulates an Src kinase-dependent activation of class I (A) phosphoinositide 3-kinase and, in turn, activation of protein kinase C Ω in neutrophils. EMBP transcription is under regulation by novel combinatorial interactions of GATA-1, PU.1, and C/EBPé isoforms.