Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Lymphocyte Signaling » LSP1 Antibodies » LSP1 Antibody (N-20): sc-17938

LSP1 Antibody (N-20): sc-17938

 |  Datasheet

(Based on data analysis)

  • LSP1 Antibody (N-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of LSP1 of human origin
  • recommended for detection of LSP1 of human origin by WB, IP, IF and ELISA
  • blocking peptide, sc-17938 P
  • See 2 citations for LSP1 Antibody (N-20)
 

See additional LSP1 Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
LSP1 Antibody (N-20) sc-17938 200 µg/ml $279
LSP1 (N-20) P sc-17938 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
LSP1 siRNA (h) sc-42899 10 µM $258
LSP1 (h)-PR sc-42899-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
LSP1 shRNA Plasmid (h) sc-42899-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
LSP1 shRNA (h) Lentiviral Particles sc-42899-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MOLT-4 Cell Lysate sc-2233 500 µg/200 µl $104
Ramos Cell Lysate sc-2216 500 µg/200 µl $104
HuT 78 Whole Cell Lysate sc-2208 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human LSP1 4046 11p15.5 NM_001013253, NM_001013254, NM_001013255, NM_002339 P33241
 153432
 

pp52 (human) or LSP1 (murine) is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein (1). However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction (2). The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia (3). The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif (4). LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis (5).

LSP1 Antibody (N-20) Product Citations
See how others have used LSP1 Antibody (N-20) and or LSP1 Antibody (N-20) conjugates.


2 total citations
Loading citations.
 
LSP1 Antibody (N-20) Data
Click on image to enlarge
sc-17938
LSP1 (N-20): sc-17938. Western blot analysis of LSP1 expression in NCI-H929 whole cell lysate.
sc-17938
LSP1 (N-20): sc-17938. Immunofluorescence staining of methanol-fixed IB4 cells showing membrane localization.
sc-17938
LSP1 (N-20): sc-17938. Western blot analysis of LSP1 expression in Ramos whole cell lysate.
Download
Datasheets
Get Adobe Acrobat Reader