epitope mapping near the N-terminus of RPA135 of human origin
recommended for detection of RPA135 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
RPA135 Background Information RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, which suggests that multiple signaling pathways are involved in carrying out Pol I transcription. RPA16, RPA40 and RPA135 are subunits of Pol I that associate with each other at an early stage of RNA Pol I assembly. RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
RPA135 (H-15)
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RPA135 (H-15): sc-17914. Western blot analysis of RPA135 expression in K-562 (A) and NIH/3T3 (B) nuclear extracts.
RPA135 (H-15): sc-17914. Western blot analysis of RPA135 expression in HeLa nuclear extract.
