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home » Transcription Regulators » Sp1, Sp2, Sp3 and Sp4 Antibody / Sp1, Sp2, Sp3 and Sp4 Antibodies » Sp2 (A-8): sc-17814

Sp2 (A-8) Antibody: sc-17814

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against amino acids 154-435 of Sp2 of human origin
  • recommended for detection of Sp2 of mouse, rat and human origin by WB, IP, IF and ELISA
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-17814 X, 200 µg/0.1 ml
 
Additional Sp1, Sp2, Sp3 and Sp4 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SP2 6668 17q21.32 NM_003110 Q02086
 601801
Mouse Sp2 78912 11 D Q9D2H6
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Sp2 (A-8) sc-17814 200 µg/ml $279
Sp2 (A-8) X sc-17814 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Sp2 siRNA (h) sc-29489 10 µM $258
Sp2 siRNA (m) sc-36543 10 µM $258
Sp2 (h)-PR sc-29489-PR 10 µM $23
Sp2 (m)-PR sc-36543-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Sp2 shRNA Plasmid (h) sc-29489-SH 20 µg $520
Sp2 shRNA Plasmid (m) sc-36543-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Sp2 shRNA (h) Lentiviral Particles sc-29489-V 200 µl $625
Sp2 shRNA (m) Lentiviral Particles sc-36543-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
K-562 nuclear extract sc-2130 1000 µg $143
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
Jurkat nuclear extract sc-2132 1000 µg $143
NIH/3T3 nuclear extract sc-2138 1000 µg $143
KNRK nuclear extract sc-2141 1000 µg $143
Sp2 (h): 293T Lysate sc-113315 100µg/200µl $205

Sp2 Background Information
The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share similar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus (1). Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes (1). Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not (2). Sp2 only weakly binds to GT boxes (2). Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues (2,3). Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the b4 subunit of neuronal nicotinic acetylcholine receptors (4). Sp3 is the only Sp member to inhibit Sp1 and Sp4 mediated transcription (5,6). The gene3 encoding human Sp2 maps to chromosome 17p32.3 (7).
Sp2 (A-8)
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sc-17814
Sp2 (A-8): sc-17814. Western blot analysis of Sp2 expression in KNRK (A), NIH/3T3 (B) and Jurkat (C) whole cell lysates.
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